KnitRegen
Making smart stroke therapy more portable
The challenge
Current estimates suggest that 1 in 4 people are likely to experience a stroke during their lifetime, and around 50% of stroke survivors experience moderate-to-severe problems using one of their arms.
Regular physiotherapy can help those with milder symptoms but for those who are more severely affected, symptoms can worsen over time. Stroke is the leading cause of disability worldwide as survivors can struggle to recover.
KnitRegen is a next-generation MedTech company that creates smart, wearable technologies to support neurological recovery from stroke or brain injury. KnitRegen’sUK-patentedsmart textiles deliver state-of-the-art muscle stimulation for continual rehabilitation outside therapy sessions, providing a new treatment for those with moderate-to-severe impairments to recover arm movement.
CPI worked with KnitRegen to develop its wearable stroke rehabilitation prototype through our Sonnet programme. We collaborated to make the technology portable – reducing its bulk from the size of a backpack to a wristband and integrating a rechargeable Bluetooth-enabled battery. We also made it safer and more energy efficient by reducing the power required to stimulate muscles.
![](https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/Screenshot-2023-05-18-at-11.46.35-2.png?w=1120&h=630&q=60&fm=jpg&fit=crop&dm=1684410901&s=388f6e1b6bacdd844e4ec87dd3b7fac9 1120w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/Screenshot-2023-05-18-at-11.46.35-2.png?w=800&h=450&q=60&fm=jpg&fit=crop&dm=1684410901&s=fbf4509f75410fa61d0682b04c208fda 800w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/Screenshot-2023-05-18-at-11.46.35-2.png?w=480&h=270&q=60&fm=jpg&fit=crop&dm=1684410901&s=c32118a94b3db0a525952d2bcbdda549 480w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/Screenshot-2023-05-18-at-11.46.35-2.png?w=960&h=540&q=45&fm=jpg&fit=crop&dm=1684410901&s=37e380212390823dbc6e593decfdd647 960w)
““CPI designed the electronics that enabled us to repackage our technology into a wearable and portable form. The collaboration has also enabled us to rigorously test all the components to meet safety standards. We can now bring this technology to more people to help with their stroke rehabilitation.””
![Dr Laura Salisbury Dr Laura Salisbury](https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/Laura.png?w=100&h=100&q=60&fm=jpg&fit=crop&dm=1684424722&s=e28ceff8eb7e3fd356cedcbc2ab8a607)
How CPI helped
- Developed approaches to improving the prototype.
- Provided electronics and firmware design expertise and bespoke electronic components.
- Conducted a feasibility study on the actuator that stimulates the muscles.
- Consulted on the future development of the product.
![](https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/KnitRegen-1920-%C3%97-1080px.png?w=1920&h=1080&q=60&fm=jpg&fit=crop&dm=1684419251&s=1540ec745a5b57d5904c2d67a9b820f8 1920w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/KnitRegen-1920-%C3%97-1080px.png?w=1120&h=630&q=60&fm=jpg&fit=crop&dm=1684419251&s=f67a1289ed5d48829ef14aabd8946acb 1120w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/KnitRegen-1920-%C3%97-1080px.png?w=800&h=450&q=60&fm=jpg&fit=crop&dm=1684419251&s=ed9334543961e327e9595b71fcaa0788 800w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/KnitRegen-1920-%C3%97-1080px.png?w=1600&h=900&q=45&fm=jpg&fit=crop&dm=1684419251&s=326396a3ff9f4a9267789dce6b9df9ad 1600w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/KnitRegen-1920-%C3%97-1080px.png?w=480&h=270&q=60&fm=jpg&fit=crop&dm=1684419251&s=1bd9c1351c03074db2b612a39d96ee62 480w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/KnitRegen-1920-%C3%97-1080px.png?w=960&h=540&q=45&fm=jpg&fit=crop&dm=1684419251&s=33301ffb699b3d9c3593c4a1dcc2b2c4 960w)
Achievements
- Streamlined electronics and key components to create a more portable wristband version of the prototype.
- Created a Bluetooth-enabled device utilising rechargeable batteries with safety controls.
- Integrated an auditory ‘click’ as an acoustic cue for the device.
- Replaced the actuator with one that uses less power to produce mechanical impulses, making it safer and more efficient.
Impact
We advanced KnitRegen’s prototype stroke rehabilitation technology to make it portable, wearable, safe, and efficient. The prototype also now combines mechanical stimuli with an audible cue.
Now in the form of a wristband, the technology can be evaluated as a medical device for people with and without mobility following a stroke. After future clinical trials, the technology could become a valuable addition to the treatment options available to those with neurological disabilities. Stroke survivors could wear the KnitRegen wristband throughout the day to enhance and reduce muscle activity for continual rehabilitation.
KnitRegen’s technology will address the health inequities that currently exist for those who have moderate-to-severe impairments following a stroke, enabling them to access rehabilitation and recover lost movement.This has the potential to be life-changing, with positive outcomes for the physical, social, and economic well-being of those affected by stroke and brain injury. In addition, its data collection will contribute valuable information on continual rehabilitation methods for other Internet of Things (IoT) devices.
Since its initial project with CPI, KnitRegen has raised £275,000 in private investment and seen its team grow by 20%, with further growth on the horizon.
Partners
![European Regional Development Fund](https://optimise2.assets-servd.host/smart-hoopoe/production/content/logos/ERDF.png?w=400&h=89&q=100&fm=png&fit=crop&dm=1686661419&s=d7c52c1afed369d71818af9a42d17e77)
![Northern Powerhouse](https://optimise2.assets-servd.host/smart-hoopoe/production/content/logos/Northern-Powerhouse.png?w=400&h=123&q=100&fm=png&fit=crop&dm=1686844948&s=497a2a4c37d0661941cdf3b96858dc1d)
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