Close-up of overlapping silver blister packs of tablets

Pack and Fill

Optimising the conveying, dispensing, and packing of powdered formulated goods

Close-up of overlapping silver blister packs of tablets

Pack and Fill

Optimising the conveying, dispensing, and packing of powdered formulated goods

Close-up of overlapping silver blister packs of tablets

Pack and Fill

Optimising the conveying, dispensing, and packing of powdered formulated goods

Close-up of overlapping silver blister packs of tablets
Close-up of overlapping silver blister packs of tablets

Developing a PAT-enabled powder filling line for process optimisation and control

CPI have developed a state-of-the-art powder filling line that uses process analytic technology (PAT) to optimise and control any packing process in real time. Combined with our advanced powder characterisation technology, CPI can address all powder filling problems, including variable pack quality or fill level, poor reliability and frequent stoppages, long change-over times between products, and lengthy trial runs when introducing new packages or products. This open-access facility is suitable for in-house and contract packers of all sizes and allows you to optimise your packing process to ensure consistent quality, saving time and money. 

Two workers in white cleanroom coveralls, masks and safety glasses operating manufacturing equipment
Two workers in white cleanroom coveralls, masks and safety glasses operating manufacturing equipment

The challenge

Powder packing operations can be notoriously challenging to optimise. Segregation of ingredients during handling, as well as powder sticking issues, mean that selection of the right equipment for storage and transport of the powder to the packing machine, and a robust process control capability are critical for a successful operation. However, powder packing is often perceived to be of low value and not worth optimisation. For this reason, a positive offset is often added to each pack to counteract variability and ensure each pack reaches the minimum weight set by law, leading to product giveaway and increased costs.

How CPI helped

  • Detailed equipment design recommendations for your particular product.

  • Demonstration of how state of the art online sensors (Process Analytical Technology) can be used for your specific powder to give an improved process control strategy.

  • Quantification of benefits achievable through equipment and process control optimisation (i.e. de-risking any capital investment decisions).

Achievements

Inputs

  • Technical expertise 

  • Access to state-of-the-art facilities and bespoke engineered equipment. 

  • Investment as part of CPI’s Formulation Strategic Projects Programme. 

Outputs

  • A state-of-the-art PAT-enabled powder filling line that can be adapted to suit a wide range of products and processes. 

  • Validation data confirming high levels of accuracy and reproducibility in all operating modes. 

  • A smaller, mobile PAT rig for initial or in-situ studies. 

Outcomes

  • Provision of a flexible, open-access facility to UK industry, capable of optimising the powder packing process, and investigating this often-overlooked part of the fast moving consumer goods supply chain. 

Close-up of a stainless steel tablet press and blister packaging machine with perforated drums and foil
Close-up of a stainless steel tablet press and blister packaging machine with perforated drums and foil
A CPI engineer at a CPI facility.

How to work with us

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Contact us today to begin your innovation journey

Contact us today to begin your innovation journey

Contact us today to begin your innovation journey