CPI Partner Stream Bio Launches New Range of CPNs™

Stream Bio Limited’s Streptavidin Conjugates can be used for the detection of various biomolecules and will complement the organisation’s current portfolio of CPN™ molecular probes. Its CPNs™ have applications in diagnostics and therapeutics, and carry the potential to be used for imaging tumours and fluorescence-guided surgery. 

These highly fluorescent, non-toxic nanoparticles are set to transform the bioimaging market with their unique brightness, exceptional stability, magnetic capability and suitability to be conjugated with a wide variety of molecules. 

The new range of molecular probes from Stream Bio have streptavidin covalently attached to fluorescent CPNs™. This allows the intense fluorescence of the CPN™ to be readily linked to a wide array of targeting molecules. 

Streptavidin is a protein with an extraordinarily high binding affinity for biotin and is commonly used to link fluorophores to primary or secondary antibodies for specific detection of a variety of proteins, protein motifs, nucleic acids and other biomolecules. 

Some of the detection protocols the Streptavidin-linked CPNs™ can be used with include flow cytometry, Western Blots, microplate assays, imaging and microscopy.

The Streptavidin linked CPNs™ are available in four wavelengths; 475nm, 510nm, 550nm and 680nm. They can be purchased from distributors 2B Scientific, in the UK, Clinisciences, in France, and Biotrends, in Germany.

Andrew Chaloner, Founding Director and Chief Executive of Stream Bio, said: ​“We are delighted to be releasing our most recent range of CPNs™. Seeing our products develop and be successfully brought to market is a justification of all the hard work put in by the team here at Stream Bio.

“I am excited to see the opportunities that this new range will bring and what the future holds for our products.” 

Established in 2015, Stream Bio has worked closely with CPI to bring its technology to commercialisation.

CPI has played an integral role in the scale-up and development of the product through the creation of proof of concept data.

Earlier this year, Stream Bio was presented with an Institute of Physics Business Start-Up Award, which was bestowed for the company’s successful implementation of physics into CPN™.

The annual Business Start-Up Award is the only recognition in the UK and Ireland that commemorates young companies on their innovative application of physics and their excellent business growth potential.