Fermentation scale-up facilities

From lab to commercialisation

Bioprocess scale-up and optimisation

The translation of a promising lab-scale innovation into a commercially viable process presents significant challenges and can be one of the most challenging steps an innovator will face. Reaching commercial readiness often involves high costs, long timelines, and complex technical hurdles.

At CPI, we provide the expertise and cutting-edge fermentation scale-up facilities needed to overcome these hurdles and create a robust, efficient and commercially viable process. Our state-of-the-art facilities support businesses developing microbial and yeast-based products, offering a full spectrum of fermentation CDMO and CMO services to help you scale with confidence.

We operate the UK’s National Industrial Biotechnology Facility, where we provide services to meet your scale-up goals, whether that’s the supply of material to support market penetration or commercialisation aims, establishing process feasibility at pilot scale, or for bioprocess optimisation, where we can optimise and de-risk your process at pilot scale. Our flexible approach is designed to meet your cost and timeline expectations.

Our offer

CPI’s National Industrial Biotechnology Facility is an open-access pilot and demonstration-scale fermentation facility to support:

  • The translation of processes from lab scale.

  • Robust testing of processes at large scale.

  • The generation of material to seed the market, gain market approval, or enable further testing.

  • Cost-effective short- and long-term contract manufacturing campaigns.

  • The optimisation of batch, fed-batch, and continuous fermentation processes.

  • The assessment of process optimisation conditions at large scale.

  • The scale-up of downstream processing (DSP) unit operations from lab-scale using a plug-and-play approach.

  • Access to pilot scale (100L, 400L, 2000L) and demonstration-scale (10,000L) fermenters.

NIBF facilities

Benefits

Our flexible approach to working with companies allows us to meet your specific innovation and commercial needs with pricing to match.

  • Proven impact across sectors: We have a track record of successfully supporting companies at all stages of development across a broad range of sectors in line with client needs.

  • Depth of experience: Ability to work across aerobic and anaerobic chassis organisms including bacteria, filamentous fungi, yeast and algae.

  • Quality assurance: Facilities are ISO9001 certified with designated labs and pilot facilities FSSC 22000 certified as well.

  • Other services: We help you to articulate your scale-up strategy, providing investors with the confidence they need.

Contract Development and Manufacturing (CDMO) Services for Fermentation

Looking to scale your bioprocess without investing in your own infrastructure? CPI offers end-to-end fermentation CDMO services designed to take your innovation from lab bench to pilot and demo scale — all under one roof.

We support partners across industrial biotechnology, alternative proteins, and specialty ingredients with:

- Fermentation process development and optimisation

- Tech transfer from laboratory to a pilot plant environment

- Pilot-scale fermentation from 10 L to 10,000 L

- Downstream processing and purification

- Analytical testing and quality control

Whether you need a full bioprocess CDMO solution or a fermentation CMO partner for contract manufacturing, our facilities and experts provide flexible, scalable support to accelerate your product to market.

We're your partner for scale-up success

Get in touch to discuss your requirements and find out how we can best support your needs.

For more information

Judith Huggan

Judith Huggan

Business Development Manager

Connect
CPI is your innovation partner to make your ideas a reality.