Protein-based biologics

Accelerating the development, optimisation, and scalability of biologic therapies.

Get to market faster with CPI

At CPI, we support the development and optimisation of protein-based biologics, including antibodies, recombinant proteins, and virus-like particles (VLPs). Our regulatory expertise, and state-of-the-art facilities enable you to accelerate from pre-clinical discovery to early-stage development with confidence and precision.

Our capabilities include cell culture, purification, digital modelling, high-throughput analytics, and GMP-ready process development, ensuring your biologic therapies are scalable, efficient, and market-ready. Whether optimising cell culture conditions, purification strategies, or stability, we provide the tools and expertise to de-risk your journey to clinical success.

Antibodies 3D model.

Protein-based biologics

Accelerating the development, optimisation, and scalability of biologic therapies.

Get to market faster with CPI

At CPI, we support the development and optimisation of protein-based biologics, including antibodies, recombinant proteins, and virus-like particles (VLPs). Our regulatory expertise, and state-of-the-art facilities enable you to accelerate from pre-clinical discovery to early-stage development with confidence and precision.

Our capabilities include cell culture, purification, digital modelling, high-throughput analytics, and GMP-ready process development, ensuring your biologic therapies are scalable, efficient, and market-ready. Whether optimising cell culture conditions, purification strategies, or stability, we provide the tools and expertise to de-risk your journey to clinical success.

Antibodies 3D model.

Protein-based biologics

Accelerating the development, optimisation, and scalability of biologic therapies.

Get to market faster with CPI

At CPI, we support the development and optimisation of protein-based biologics, including antibodies, recombinant proteins, and virus-like particles (VLPs). Our regulatory expertise, and state-of-the-art facilities enable you to accelerate from pre-clinical discovery to early-stage development with confidence and precision.

Our capabilities include cell culture, purification, digital modelling, high-throughput analytics, and GMP-ready process development, ensuring your biologic therapies are scalable, efficient, and market-ready. Whether optimising cell culture conditions, purification strategies, or stability, we provide the tools and expertise to de-risk your journey to clinical success.

  • SGS Quay Pharma
  • BoobyBiome
  • RNAssist
  • Intract Pharma
  • Pharmidex
  • AstraZeneca

What we offer

Whether you need technical expertise, lab-based development, process optimisation, or regulatory guidance, our tailored approach ensures you have the right support at every stage.

What we offer

Whether you need technical expertise, lab-based development, process optimisation, or regulatory guidance, our tailored approach ensures you have the right support at every stage.

What we offer

Whether you need technical expertise, lab-based development, process optimisation, or regulatory guidance, our tailored approach ensures you have the right support at every stage.

Antibody process development and formulation

We provide tailored solutions for antibody production and characterisation, supporting pre-clinical discovery through early-stage development. Our expertise includes:

  • Cell bank generation and transient expression development.

  • Upstream and downstream processing at scales up to 200L.

  • Mammalian expression platforms (CHO, HEK293, MSCs).

  • Advanced analytical characterisation including QTOF mass spectrometry, SEC-MALS, and glycan analysis.

  • High-throughput bioprocessing with AMBR bioreactors.

 These capabilities ensure optimal titres, purity, and molecular structure, supporting early-stage toxicology, formulation development, and material supply.

Antibody process development and formulation

We provide tailored solutions for antibody production and characterisation, supporting pre-clinical discovery through early-stage development. Our expertise includes:

  • Cell bank generation and transient expression development.

  • Upstream and downstream processing at scales up to 200L.

  • Mammalian expression platforms (CHO, HEK293, MSCs).

  • Advanced analytical characterisation including QTOF mass spectrometry, SEC-MALS, and glycan analysis.

  • High-throughput bioprocessing with AMBR bioreactors.

 These capabilities ensure optimal titres, purity, and molecular structure, supporting early-stage toxicology, formulation development, and material supply.

Recombinant protein and VLP process development

We accelerate recombinant protein and VLP production with advanced bioprocessing expertise:

  • Microbial and mammalian expression systems – E. coli, S. cerevisiae, P. Pastoris, B. subtilis, CHO, HEK293 and MSCs.

  • Cell-free protein synthesis for rapid prototyping.

  • Plasmid stability testing and strain selection for enhanced yield and purity.

  • Process development at bench to 100L scale.

  • Downstream purification strategies – optimising recovery and process efficiency.

These capabilities support early-stage discovery, toxicology evaluations, and high-quality material supply for preclinical studies.

Recombinant protein and VLP process development

We accelerate recombinant protein and VLP production with advanced bioprocessing expertise:

  • Microbial and mammalian expression systems – E. coli, S. cerevisiae, P. Pastoris, B. subtilis, CHO, HEK293 and MSCs.

  • Cell-free protein synthesis for rapid prototyping.

  • Plasmid stability testing and strain selection for enhanced yield and purity.

  • Process development at bench to 100L scale.

  • Downstream purification strategies – optimising recovery and process efficiency.

These capabilities support early-stage discovery, toxicology evaluations, and high-quality material supply for preclinical studies.

Equipment and technology testing (alpha and beta)

De-risk your innovative technology with our industry-leading expertise in benchmarking and process validation. Whether you are a technology vendor in the development stage or a business evaluating a technical piece of equipment, we provide objective and reliable testing in industry-relevant environments.

  • Alpha and beta testing: Benchmarking new biologics technologies in real-world environments.

  • Process validation studies: Assessing reproducibility, manufacturability, and yield consistency.

  • Side-by-side technology comparisons: Evaluating competing bioprocessing approaches.

  • Proof-of-concept testing: Ensuring scalable, cost-effective, and high-yield workflows.

Our expertise ensures objective, data-driven validation of new bioprocessing technologies, helping companies make informed investment decisions.

Equipment and technology testing (alpha and beta)

De-risk your innovative technology with our industry-leading expertise in benchmarking and process validation. Whether you are a technology vendor in the development stage or a business evaluating a technical piece of equipment, we provide objective and reliable testing in industry-relevant environments.

  • Alpha and beta testing: Benchmarking new biologics technologies in real-world environments.

  • Process validation studies: Assessing reproducibility, manufacturability, and yield consistency.

  • Side-by-side technology comparisons: Evaluating competing bioprocessing approaches.

  • Proof-of-concept testing: Ensuring scalable, cost-effective, and high-yield workflows.

Our expertise ensures objective, data-driven validation of new bioprocessing technologies, helping companies make informed investment decisions.

Protein-based biologics applications

We support innovation across a wide range of biologics applications.

Gloved hands drawing liquid from a vial into a syringe with a pink needle hub.

Protein-based biologics applications

We support innovation across a wide range of biologics applications.

Gloved hands drawing liquid from a vial into a syringe with a pink needle hub.

Protein-based biologics applications

We support innovation across a wide range of biologics applications.

Gloved hands drawing liquid from a vial into a syringe with a pink needle hub.

How we support you

From discovery to commercialisation, we enable scalable, cost-effective, and regulatory-compliant pharmaceutical innovations.

How we support you

From discovery to commercialisation, we enable scalable, cost-effective, and regulatory-compliant pharmaceutical innovations.

How we support you

From discovery to commercialisation, we enable scalable, cost-effective, and regulatory-compliant pharmaceutical innovations.

Demonstrate the benefits of your biologics innovation

We provide the expertise, tools, and infrastructure to accelerate early-stage development and support investment readiness with: 

  • Rapid, cost-effective product and process development for securing early-stage funding.

  • Evaluation of biologics function in industry-relevant settings for investor confidence.

  • Optimisation of new biologics integration into product pipelines for competitive advantage.

Demonstrate the benefits of your biologics innovation

We provide the expertise, tools, and infrastructure to accelerate early-stage development and support investment readiness with: 

  • Rapid, cost-effective product and process development for securing early-stage funding.

  • Evaluation of biologics function in industry-relevant settings for investor confidence.

  • Optimisation of new biologics integration into product pipelines for competitive advantage.

Prove manufacturability and scalability

Ensure your biologic therapies are reproducible, scalable, and sustainable with our process development expertise. With CPI, you can access:

  • Early-stage manufacturability assessments to evaluate production feasibility.

  • Process optimisation to enhance efficiency, yield, and cost-effectiveness.

  • Scalable biomanufacturing processes for clinical and commercial readiness.

Prove manufacturability and scalability

Ensure your biologic therapies are reproducible, scalable, and sustainable with our process development expertise. With CPI, you can access:

  • Early-stage manufacturability assessments to evaluate production feasibility.

  • Process optimisation to enhance efficiency, yield, and cost-effectiveness.

  • Scalable biomanufacturing processes for clinical and commercial readiness.

Assess and demonstrate commercial viability

We provide data-driven insights and process validation to secure funding and commercial partnerships. We support with:

  • Commercial feasibility assessments for biologics production.

  • Validation of scale-up processes to attract investment and licensing opportunities.

  • Transitioning from pre-clinical development to market launch.

Assess and demonstrate commercial viability

We provide data-driven insights and process validation to secure funding and commercial partnerships. We support with:

  • Commercial feasibility assessments for biologics production.

  • Validation of scale-up processes to attract investment and licensing opportunities.

  • Transitioning from pre-clinical development to market launch.

Streamline regulatory compliance

We help to de-risk regulatory pathways, ensuring compliance with global standards. Our experts provide:

  • GMP-ready infrastructure for biologics manufacturing.

  • Regulatory support for EMA, FDA, and MHRA approvals.

  • Quality assurance and documentation to reduce risk and accelerate time-to-market.

Streamline regulatory compliance

We help to de-risk regulatory pathways, ensuring compliance with global standards. Our experts provide:

  • GMP-ready infrastructure for biologics manufacturing.

  • Regulatory support for EMA, FDA, and MHRA approvals.

  • Quality assurance and documentation to reduce risk and accelerate time-to-market.

Secure strategic partnerships

As a trusted UK government partner, we have built a broad network across global leaders, emerging companies, large corporates, healthcare, and academia. We facilitate:

  • Access to world-class biologics manufacturers and academic institutions.

  • Connections to supply chains and commercial production partners.

  • Strategic collaborations for long-term biologics market growth.

Secure strategic partnerships

As a trusted UK government partner, we have built a broad network across global leaders, emerging companies, large corporates, healthcare, and academia. We facilitate:

  • Access to world-class biologics manufacturers and academic institutions.

  • Connections to supply chains and commercial production partners.

  • Strategic collaborations for long-term biologics market growth.

  • Stainless steel process equipment skid installed in a pharmaceutical cleanroom.
    White oval tablets in the tray of a pharmaceutical counting and inspection machine.
  • Gowned scientist using a pipette to transfer a sample into a tube inside a laminar flow hood.
    CPI scientist in a lab coat and safety glasses using a pipette at a laboratory bench.
  • CPI scientist in a blue lab coat operating an ambr 250 automated bioreactor system with a tablet.
  • Row of capped glass vials moving along a pharmaceutical filling line.
    CPI scientist in safety glasses using a pipette to handle a pink sample in a laboratory.
  • CPI scientist drawing a process diagram on a glass screen in a laboratory.
    CPI scientists in blue lab coats operating analytical equipment in a laboratory.
  • Gloved hand placing a strip of PCR tubes containing blue liquid into a thermal cycler.
  • Stainless steel process equipment skid installed in a pharmaceutical cleanroom.
    White oval tablets in the tray of a pharmaceutical counting and inspection machine.
  • Gowned scientist using a pipette to transfer a sample into a tube inside a laminar flow hood.
    CPI scientist in a lab coat and safety glasses using a pipette at a laboratory bench.
  • CPI scientist in a blue lab coat operating an ambr 250 automated bioreactor system with a tablet.
  • Row of capped glass vials moving along a pharmaceutical filling line.
    CPI scientist in safety glasses using a pipette to handle a pink sample in a laboratory.
  • CPI scientist drawing a process diagram on a glass screen in a laboratory.
    CPI scientists in blue lab coats operating analytical equipment in a laboratory.
  • Gloved hand placing a strip of PCR tubes containing blue liquid into a thermal cycler.
  • Stainless steel process equipment skid installed in a pharmaceutical cleanroom.
    White oval tablets in the tray of a pharmaceutical counting and inspection machine.
  • Gowned scientist using a pipette to transfer a sample into a tube inside a laminar flow hood.
    CPI scientist in a lab coat and safety glasses using a pipette at a laboratory bench.
  • CPI scientist in a blue lab coat operating an ambr 250 automated bioreactor system with a tablet.
  • Row of capped glass vials moving along a pharmaceutical filling line.
    CPI scientist in safety glasses using a pipette to handle a pink sample in a laboratory.
  • CPI scientist drawing a process diagram on a glass screen in a laboratory.
    CPI scientists in blue lab coats operating analytical equipment in a laboratory.
  • Gloved hand placing a strip of PCR tubes containing blue liquid into a thermal cycler.
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Trusted by leading organisations

Showing slide 1 of 1
BoobyBiome

CPI was an excellent partner, aiding in demonstrating the manufacturing feasibility of our top bacterial candidates and distinguishing between strains in co-cultures. Their facilities in Darlington were impressive, facilitating rapid data generation. We’re now collaborating with CPI again to complete our preclinical program and prepare for the launch of our symbiotic supplement. I am excited to see this hard work translate into improved health for the next generation of infants!

Headshot of Lydia Mapstone, CEO

Lydia Mapstone

CEO

RNAssist

With CPI, we’ve shown that ambient-stable vaccine formulations are achievable, enabling global vaccine equity. CPI’s expertise, including proving the large-scale manufacturability of our TheraPHIX™ stabiliser, has advanced us far faster than we could have managed alone, giving us the credibility to aim for widespread adoption by vaccine manufacturers worldwide.

Headshot of Andrew Goldsborough, CEO

Andrew Goldsborough

CEO

Intract Pharma

Thanks to the expertise in drug development and manufacture brought by the colleagues from Quay, CPI and Pharmidex, we successfully developed a scalable manufacturing process for oral antibody products.

Headshot of Silvia Matiz, Formulation Scientist

Silvia Matiz

Formulation Scientist

AstraZeneca

With digital tools we can build in operational excellence right from the start of pharmaceutical development, improve product robustness, and drive more efficient manufacturing processes to deliver more medicines to more patients, more quickly.

Headshot of Sophie Bailes, Director Digital Transformation

Sophie Bailes

Director Digital Transformation

4basebio

CPI helped us accelerate a vital aspect of our manufacturing process to expedite our journey towards a clinical product. We’ve made significant progress in our GMP manufacturing capabilities, leading to our first DNA sales and increased interest in our products from partners and client base.

Headshot of Carmen Mañas Torres, Team Leader in Synthetic DNA Purification

Carmen Mañas Torres

Team Leader in Synthetic DNA Purification

Immune Boost Clinic

Manufacturing is just one part of the process, and CPI does so much more than just that. Growing mycolicibacteria consistently and reliably to food grade standard and combining them with other ingredients is difficult and requires attention to detail, expertise and experience from your partner.

Headshot of Tim Dye, Senior Scientific and Operations Advisor

Tim Dye

Senior Scientific and Operations Advisor

Trusted by leading organisations

Showing slide 1 of 1
BoobyBiome

CPI was an excellent partner, aiding in demonstrating the manufacturing feasibility of our top bacterial candidates and distinguishing between strains in co-cultures. Their facilities in Darlington were impressive, facilitating rapid data generation. We’re now collaborating with CPI again to complete our preclinical program and prepare for the launch of our symbiotic supplement. I am excited to see this hard work translate into improved health for the next generation of infants!

Headshot of Lydia Mapstone, CEO

Lydia Mapstone

CEO

RNAssist

With CPI, we’ve shown that ambient-stable vaccine formulations are achievable, enabling global vaccine equity. CPI’s expertise, including proving the large-scale manufacturability of our TheraPHIX™ stabiliser, has advanced us far faster than we could have managed alone, giving us the credibility to aim for widespread adoption by vaccine manufacturers worldwide.

Headshot of Andrew Goldsborough, CEO

Andrew Goldsborough

CEO

Intract Pharma

Thanks to the expertise in drug development and manufacture brought by the colleagues from Quay, CPI and Pharmidex, we successfully developed a scalable manufacturing process for oral antibody products.

Headshot of Silvia Matiz, Formulation Scientist

Silvia Matiz

Formulation Scientist

AstraZeneca

With digital tools we can build in operational excellence right from the start of pharmaceutical development, improve product robustness, and drive more efficient manufacturing processes to deliver more medicines to more patients, more quickly.

Headshot of Sophie Bailes, Director Digital Transformation

Sophie Bailes

Director Digital Transformation

4basebio

CPI helped us accelerate a vital aspect of our manufacturing process to expedite our journey towards a clinical product. We’ve made significant progress in our GMP manufacturing capabilities, leading to our first DNA sales and increased interest in our products from partners and client base.

Headshot of Carmen Mañas Torres, Team Leader in Synthetic DNA Purification

Carmen Mañas Torres

Team Leader in Synthetic DNA Purification

Immune Boost Clinic

Manufacturing is just one part of the process, and CPI does so much more than just that. Growing mycolicibacteria consistently and reliably to food grade standard and combining them with other ingredients is difficult and requires attention to detail, expertise and experience from your partner.

Headshot of Tim Dye, Senior Scientific and Operations Advisor

Tim Dye

Senior Scientific and Operations Advisor

Trusted by leading organisations

Showing slide 1 of 1
BoobyBiome

CPI was an excellent partner, aiding in demonstrating the manufacturing feasibility of our top bacterial candidates and distinguishing between strains in co-cultures. Their facilities in Darlington were impressive, facilitating rapid data generation. We’re now collaborating with CPI again to complete our preclinical program and prepare for the launch of our symbiotic supplement. I am excited to see this hard work translate into improved health for the next generation of infants!

Headshot of Lydia Mapstone, CEO

Lydia Mapstone

CEO

RNAssist

With CPI, we’ve shown that ambient-stable vaccine formulations are achievable, enabling global vaccine equity. CPI’s expertise, including proving the large-scale manufacturability of our TheraPHIX™ stabiliser, has advanced us far faster than we could have managed alone, giving us the credibility to aim for widespread adoption by vaccine manufacturers worldwide.

Headshot of Andrew Goldsborough, CEO

Andrew Goldsborough

CEO

Intract Pharma

Thanks to the expertise in drug development and manufacture brought by the colleagues from Quay, CPI and Pharmidex, we successfully developed a scalable manufacturing process for oral antibody products.

Headshot of Silvia Matiz, Formulation Scientist

Silvia Matiz

Formulation Scientist

AstraZeneca

With digital tools we can build in operational excellence right from the start of pharmaceutical development, improve product robustness, and drive more efficient manufacturing processes to deliver more medicines to more patients, more quickly.

Headshot of Sophie Bailes, Director Digital Transformation

Sophie Bailes

Director Digital Transformation

4basebio

CPI helped us accelerate a vital aspect of our manufacturing process to expedite our journey towards a clinical product. We’ve made significant progress in our GMP manufacturing capabilities, leading to our first DNA sales and increased interest in our products from partners and client base.

Headshot of Carmen Mañas Torres, Team Leader in Synthetic DNA Purification

Carmen Mañas Torres

Team Leader in Synthetic DNA Purification

Immune Boost Clinic

Manufacturing is just one part of the process, and CPI does so much more than just that. Growing mycolicibacteria consistently and reliably to food grade standard and combining them with other ingredients is difficult and requires attention to detail, expertise and experience from your partner.

Headshot of Tim Dye, Senior Scientific and Operations Advisor

Tim Dye

Senior Scientific and Operations Advisor

Get in touch

Get in touch

Get in touch