Viral vectors and viral vaccines

Accelerating process development and scale-up for next-generation gene therapies and vaccines.

Get to market faster with CPI

At CPI, we support the development, scale-up, and characterisation of viral vectors and viral vaccines, enabling efficient, high-quality production for gene therapies, oncolytic viruses, and advanced vaccine platforms.

With expertise in upstream and downstream bioprocessing, analytical development, and regulatory compliance, we help you optimise viral vector manufacturing, ensuring stability, scalability, and clinical readiness.

Viral structure.

Viral vectors and viral vaccines

Accelerating process development and scale-up for next-generation gene therapies and vaccines.

Get to market faster with CPI

At CPI, we support the development, scale-up, and characterisation of viral vectors and viral vaccines, enabling efficient, high-quality production for gene therapies, oncolytic viruses, and advanced vaccine platforms.

With expertise in upstream and downstream bioprocessing, analytical development, and regulatory compliance, we help you optimise viral vector manufacturing, ensuring stability, scalability, and clinical readiness.

Viral structure.

Viral vectors and viral vaccines

Accelerating process development and scale-up for next-generation gene therapies and vaccines.

Get to market faster with CPI

At CPI, we support the development, scale-up, and characterisation of viral vectors and viral vaccines, enabling efficient, high-quality production for gene therapies, oncolytic viruses, and advanced vaccine platforms.

With expertise in upstream and downstream bioprocessing, analytical development, and regulatory compliance, we help you optimise viral vector manufacturing, ensuring stability, scalability, and clinical readiness.

  • SGS Quay Pharma
  • BoobyBiome
  • RNAssist
  • Intract Pharma
  • Pharmidex
  • AstraZeneca

What we offer

Whether you need technical expertise, lab-based development, process optimisation, or regulatory guidance, our tailored approach ensures you have the right support at every stage.

What we offer

Whether you need technical expertise, lab-based development, process optimisation, or regulatory guidance, our tailored approach ensures you have the right support at every stage.

What we offer

Whether you need technical expertise, lab-based development, process optimisation, or regulatory guidance, our tailored approach ensures you have the right support at every stage.

AAV, lentivirus and viral vaccine process development

Optimise the development and scale-up of viral vectors and vaccines with our expertise:

  • Upstream process development using transient transfection or stable cell lines.

  • High-throughput AMBR bioreactor systems for process optimisation.

  • Downstream purification and formulation to improve titre and stability.

  • Research cell bank generation and characterisation.

  • Process scalability up to 200L bioreactor systems. 

These capabilities enhance yield, purity, and process consistency, supporting gene therapies and vaccine development.

AAV, lentivirus and viral vaccine process development

Optimise the development and scale-up of viral vectors and vaccines with our expertise:

  • Upstream process development using transient transfection or stable cell lines.

  • High-throughput AMBR bioreactor systems for process optimisation.

  • Downstream purification and formulation to improve titre and stability.

  • Research cell bank generation and characterisation.

  • Process scalability up to 200L bioreactor systems. 

These capabilities enhance yield, purity, and process consistency, supporting gene therapies and vaccine development.

Viral vector technology benchmarking and validation

De-risk your innovative technology with our independent testing and benchmarking services:

  • Alpha and beta testing of viral vector production platforms.

  • Side-by-side comparisons of process efficiency and scalability.

  • Proof-of-concept studies for novel viral vector technologies.

  • Analytical characterisation of viral titres, potency, and integrity.

Our expertise ensures objective, data-driven validation of novel viral vector technologies, helping you to demonstrate performance, build industry credibility, and accelerate market adoption.

Viral vector technology benchmarking and validation

De-risk your innovative technology with our independent testing and benchmarking services:

  • Alpha and beta testing of viral vector production platforms.

  • Side-by-side comparisons of process efficiency and scalability.

  • Proof-of-concept studies for novel viral vector technologies.

  • Analytical characterisation of viral titres, potency, and integrity.

Our expertise ensures objective, data-driven validation of novel viral vector technologies, helping you to demonstrate performance, build industry credibility, and accelerate market adoption.

Analytical development and characterisation

Ensure the quality, consistency, and stability of viral vectors and vaccines with our advanced analytical capabilities:

  • Purity and titre assessments using ddPCR, ELISA, and SEC-MALS.

  • Empty/full capsid ratio analysis for AAV vectors.

  • Stability and degradation studies under real-time conditions.

  • High-resolution characterisation using next-generation sequencing (NGS).

These capabilities ensure regulatory compliance and optimise batch-to-batch consistency.

Analytical development and characterisation

Ensure the quality, consistency, and stability of viral vectors and vaccines with our advanced analytical capabilities:

  • Purity and titre assessments using ddPCR, ELISA, and SEC-MALS.

  • Empty/full capsid ratio analysis for AAV vectors.

  • Stability and degradation studies under real-time conditions.

  • High-resolution characterisation using next-generation sequencing (NGS).

These capabilities ensure regulatory compliance and optimise batch-to-batch consistency.

Viral vectors and viral vaccines applications

We enable innovation across a wide range of viral vector applications.

Gloved hands drawing blue liquid from a vial into a syringe.

Viral vectors and viral vaccines applications

We enable innovation across a wide range of viral vector applications.

Gloved hands drawing blue liquid from a vial into a syringe.

Viral vectors and viral vaccines applications

We enable innovation across a wide range of viral vector applications.

Gloved hands drawing blue liquid from a vial into a syringe.

How we support you

From discovery to commercialisation, we enable scalable, cost-effective, and regulatory-compliant pharmaceutical innovations.

How we support you

From discovery to commercialisation, we enable scalable, cost-effective, and regulatory-compliant pharmaceutical innovations.

How we support you

From discovery to commercialisation, we enable scalable, cost-effective, and regulatory-compliant pharmaceutical innovations.

Demonstrate the benefits of your viral vector innovation

Leverage our expertise to accelerate early-stage viral vector and vaccine development with:

  • Fast, cost-effective viral vector process development for securing funding.

  • Evaluation of your viral vectors in industry-relevant settings.

  • Integration of viral vector technologies into gene therapy pipelines.

Demonstrate the benefits of your viral vector innovation

Leverage our expertise to accelerate early-stage viral vector and vaccine development with:

  • Fast, cost-effective viral vector process development for securing funding.

  • Evaluation of your viral vectors in industry-relevant settings.

  • Integration of viral vector technologies into gene therapy pipelines.

Prove manufacturability and scalability

Ensure your viral vectors are scalable and reproducible with our expertise. With CPI, you can access:

  • Early-stage manufacturability assessments for gene therapies and vaccines.

  • Process optimisation for yield, stability, and cost-effectiveness.

  • Scalable production methods supporting preclinical and clinical development.

Prove manufacturability and scalability

Ensure your viral vectors are scalable and reproducible with our expertise. With CPI, you can access:

  • Early-stage manufacturability assessments for gene therapies and vaccines.

  • Process optimisation for yield, stability, and cost-effectiveness.

  • Scalable production methods supporting preclinical and clinical development.

Assess and demonstrate commercial viability

We provide data-driven insights and process validation to secure funding and commercial partnerships. We support with:

  • Commercial feasibility assessments for viral vector production.

  • Evaluation of scale-up processes to secure funding and partnerships.

  • Transitioning from preclinical development to market launch.

Assess and demonstrate commercial viability

We provide data-driven insights and process validation to secure funding and commercial partnerships. We support with:

  • Commercial feasibility assessments for viral vector production.

  • Evaluation of scale-up processes to secure funding and partnerships.

  • Transitioning from preclinical development to market launch.

Streamline regulatory compliance

We help to de-risk regulatory pathways, ensuring compliance with global standards. Our experts provide:

  • GMP-compliant viral vector manufacturing facilities.

  • Regulatory support for EMA, FDA, and MHRA approvals.

  • Quality assurance and documentation to mitigate risk.

Streamline regulatory compliance

We help to de-risk regulatory pathways, ensuring compliance with global standards. Our experts provide:

  • GMP-compliant viral vector manufacturing facilities.

  • Regulatory support for EMA, FDA, and MHRA approvals.

  • Quality assurance and documentation to mitigate risk.

Secure strategic partnerships

As a trusted UK government partner, we have built a broad network across global leaders, emerging companies, large corporates, healthcare, and academia. We facilitate:

  • Access to world-class gene therapy and vaccine manufacturing partners.

  • Robust supply chains for viral vector production.

  • Collaborative projects tackling industry-wide challenges.

Secure strategic partnerships

As a trusted UK government partner, we have built a broad network across global leaders, emerging companies, large corporates, healthcare, and academia. We facilitate:

  • Access to world-class gene therapy and vaccine manufacturing partners.

  • Robust supply chains for viral vector production.

  • Collaborative projects tackling industry-wide challenges.

  • Stainless steel process equipment skid installed in a pharmaceutical cleanroom.
    White oval tablets in the tray of a pharmaceutical counting and inspection machine.
  • Gowned scientist using a pipette to transfer a sample into a tube inside a laminar flow hood.
    CPI scientist in a lab coat and safety glasses using a pipette at a laboratory bench.
  • CPI scientist in a blue lab coat operating an ambr 250 automated bioreactor system with a tablet.
  • Row of capped glass vials moving along a pharmaceutical filling line.
    CPI scientist in safety glasses using a pipette to handle a pink sample in a laboratory.
  • CPI scientist drawing a process diagram on a glass screen in a laboratory.
    CPI scientists in blue lab coats operating analytical equipment in a laboratory.
  • Gloved hand placing a strip of PCR tubes containing blue liquid into a thermal cycler.
  • Stainless steel process equipment skid installed in a pharmaceutical cleanroom.
    White oval tablets in the tray of a pharmaceutical counting and inspection machine.
  • Gowned scientist using a pipette to transfer a sample into a tube inside a laminar flow hood.
    CPI scientist in a lab coat and safety glasses using a pipette at a laboratory bench.
  • CPI scientist in a blue lab coat operating an ambr 250 automated bioreactor system with a tablet.
  • Row of capped glass vials moving along a pharmaceutical filling line.
    CPI scientist in safety glasses using a pipette to handle a pink sample in a laboratory.
  • CPI scientist drawing a process diagram on a glass screen in a laboratory.
    CPI scientists in blue lab coats operating analytical equipment in a laboratory.
  • Gloved hand placing a strip of PCR tubes containing blue liquid into a thermal cycler.
  • Stainless steel process equipment skid installed in a pharmaceutical cleanroom.
    White oval tablets in the tray of a pharmaceutical counting and inspection machine.
  • Gowned scientist using a pipette to transfer a sample into a tube inside a laminar flow hood.
    CPI scientist in a lab coat and safety glasses using a pipette at a laboratory bench.
  • CPI scientist in a blue lab coat operating an ambr 250 automated bioreactor system with a tablet.
  • Row of capped glass vials moving along a pharmaceutical filling line.
    CPI scientist in safety glasses using a pipette to handle a pink sample in a laboratory.
  • CPI scientist drawing a process diagram on a glass screen in a laboratory.
    CPI scientists in blue lab coats operating analytical equipment in a laboratory.
  • Gloved hand placing a strip of PCR tubes containing blue liquid into a thermal cycler.
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Trusted by leading organisations

Showing slide 1 of 1
BoobyBiome

CPI was an excellent partner, aiding in demonstrating the manufacturing feasibility of our top bacterial candidates and distinguishing between strains in co-cultures. Their facilities in Darlington were impressive, facilitating rapid data generation. We’re now collaborating with CPI again to complete our preclinical program and prepare for the launch of our symbiotic supplement. I am excited to see this hard work translate into improved health for the next generation of infants!

Headshot of Lydia Mapstone, CEO

Lydia Mapstone

CEO

RNAssist

With CPI, we’ve shown that ambient-stable vaccine formulations are achievable, enabling global vaccine equity. CPI’s expertise, including proving the large-scale manufacturability of our TheraPHIX™ stabiliser, has advanced us far faster than we could have managed alone, giving us the credibility to aim for widespread adoption by vaccine manufacturers worldwide.

Headshot of Andrew Goldsborough, CEO

Andrew Goldsborough

CEO

Intract Pharma

Thanks to the expertise in drug development and manufacture brought by the colleagues from Quay, CPI and Pharmidex, we successfully developed a scalable manufacturing process for oral antibody products.

Headshot of Silvia Matiz, Formulation Scientist

Silvia Matiz

Formulation Scientist

AstraZeneca

With digital tools we can build in operational excellence right from the start of pharmaceutical development, improve product robustness, and drive more efficient manufacturing processes to deliver more medicines to more patients, more quickly.

Headshot of Sophie Bailes, Director Digital Transformation

Sophie Bailes

Director Digital Transformation

4basebio

CPI helped us accelerate a vital aspect of our manufacturing process to expedite our journey towards a clinical product. We’ve made significant progress in our GMP manufacturing capabilities, leading to our first DNA sales and increased interest in our products from partners and client base.

Headshot of Carmen Mañas Torres, Team Leader in Synthetic DNA Purification

Carmen Mañas Torres

Team Leader in Synthetic DNA Purification

Immune Boost Clinic

Manufacturing is just one part of the process, and CPI does so much more than just that. Growing mycolicibacteria consistently and reliably to food grade standard and combining them with other ingredients is difficult and requires attention to detail, expertise and experience from your partner.

Headshot of Tim Dye, Senior Scientific and Operations Advisor

Tim Dye

Senior Scientific and Operations Advisor

Trusted by leading organisations

Showing slide 1 of 1
BoobyBiome

CPI was an excellent partner, aiding in demonstrating the manufacturing feasibility of our top bacterial candidates and distinguishing between strains in co-cultures. Their facilities in Darlington were impressive, facilitating rapid data generation. We’re now collaborating with CPI again to complete our preclinical program and prepare for the launch of our symbiotic supplement. I am excited to see this hard work translate into improved health for the next generation of infants!

Headshot of Lydia Mapstone, CEO

Lydia Mapstone

CEO

RNAssist

With CPI, we’ve shown that ambient-stable vaccine formulations are achievable, enabling global vaccine equity. CPI’s expertise, including proving the large-scale manufacturability of our TheraPHIX™ stabiliser, has advanced us far faster than we could have managed alone, giving us the credibility to aim for widespread adoption by vaccine manufacturers worldwide.

Headshot of Andrew Goldsborough, CEO

Andrew Goldsborough

CEO

Intract Pharma

Thanks to the expertise in drug development and manufacture brought by the colleagues from Quay, CPI and Pharmidex, we successfully developed a scalable manufacturing process for oral antibody products.

Headshot of Silvia Matiz, Formulation Scientist

Silvia Matiz

Formulation Scientist

AstraZeneca

With digital tools we can build in operational excellence right from the start of pharmaceutical development, improve product robustness, and drive more efficient manufacturing processes to deliver more medicines to more patients, more quickly.

Headshot of Sophie Bailes, Director Digital Transformation

Sophie Bailes

Director Digital Transformation

4basebio

CPI helped us accelerate a vital aspect of our manufacturing process to expedite our journey towards a clinical product. We’ve made significant progress in our GMP manufacturing capabilities, leading to our first DNA sales and increased interest in our products from partners and client base.

Headshot of Carmen Mañas Torres, Team Leader in Synthetic DNA Purification

Carmen Mañas Torres

Team Leader in Synthetic DNA Purification

Immune Boost Clinic

Manufacturing is just one part of the process, and CPI does so much more than just that. Growing mycolicibacteria consistently and reliably to food grade standard and combining them with other ingredients is difficult and requires attention to detail, expertise and experience from your partner.

Headshot of Tim Dye, Senior Scientific and Operations Advisor

Tim Dye

Senior Scientific and Operations Advisor

Trusted by leading organisations

Showing slide 1 of 1
BoobyBiome

CPI was an excellent partner, aiding in demonstrating the manufacturing feasibility of our top bacterial candidates and distinguishing between strains in co-cultures. Their facilities in Darlington were impressive, facilitating rapid data generation. We’re now collaborating with CPI again to complete our preclinical program and prepare for the launch of our symbiotic supplement. I am excited to see this hard work translate into improved health for the next generation of infants!

Headshot of Lydia Mapstone, CEO

Lydia Mapstone

CEO

RNAssist

With CPI, we’ve shown that ambient-stable vaccine formulations are achievable, enabling global vaccine equity. CPI’s expertise, including proving the large-scale manufacturability of our TheraPHIX™ stabiliser, has advanced us far faster than we could have managed alone, giving us the credibility to aim for widespread adoption by vaccine manufacturers worldwide.

Headshot of Andrew Goldsborough, CEO

Andrew Goldsborough

CEO

Intract Pharma

Thanks to the expertise in drug development and manufacture brought by the colleagues from Quay, CPI and Pharmidex, we successfully developed a scalable manufacturing process for oral antibody products.

Headshot of Silvia Matiz, Formulation Scientist

Silvia Matiz

Formulation Scientist

AstraZeneca

With digital tools we can build in operational excellence right from the start of pharmaceutical development, improve product robustness, and drive more efficient manufacturing processes to deliver more medicines to more patients, more quickly.

Headshot of Sophie Bailes, Director Digital Transformation

Sophie Bailes

Director Digital Transformation

4basebio

CPI helped us accelerate a vital aspect of our manufacturing process to expedite our journey towards a clinical product. We’ve made significant progress in our GMP manufacturing capabilities, leading to our first DNA sales and increased interest in our products from partners and client base.

Headshot of Carmen Mañas Torres, Team Leader in Synthetic DNA Purification

Carmen Mañas Torres

Team Leader in Synthetic DNA Purification

Immune Boost Clinic

Manufacturing is just one part of the process, and CPI does so much more than just that. Growing mycolicibacteria consistently and reliably to food grade standard and combining them with other ingredients is difficult and requires attention to detail, expertise and experience from your partner.

Headshot of Tim Dye, Senior Scientific and Operations Advisor

Tim Dye

Senior Scientific and Operations Advisor

Get in touch

Get in touch

Get in touch