Bioprocess development and scale-up

Digitalisation and bioprocess optimisation

Advanced modelling, AI-driven optimisation, and real-time analytics to accelerate your bioprocess commercialisation.

Get in touch

View capabilities

From real-time insight to robust scale-up

We integrate advanced digitalisation techniques and intelligent analytics into bioprocess development, significantly enhancing process predictability, consistency, and efficiency.

Our expertise in process modelling, machine learning, and inline analytical technologies enables real-time insights, helping you optimise bioprocesses, minimise risks, and accelerate your path from lab-scale research to commercial-scale production. 

CPI expert using a computer to monitor and control equipment.

Bioprocess development and scale-up

Digitalisation and bioprocess optimisation

Advanced modelling, AI-driven optimisation, and real-time analytics to accelerate your bioprocess commercialisation.

Get in touch

View capabilities

From real-time insight to robust scale-up

We integrate advanced digitalisation techniques and intelligent analytics into bioprocess development, significantly enhancing process predictability, consistency, and efficiency.

Our expertise in process modelling, machine learning, and inline analytical technologies enables real-time insights, helping you optimise bioprocesses, minimise risks, and accelerate your path from lab-scale research to commercial-scale production. 

CPI expert using a computer to monitor and control equipment.

Bioprocess development and scale-up

Digitalisation and bioprocess optimisation

Advanced modelling, AI-driven optimisation, and real-time analytics to accelerate your bioprocess commercialisation.

Get in touch

View capabilities

From real-time insight to robust scale-up

We integrate advanced digitalisation techniques and intelligent analytics into bioprocess development, significantly enhancing process predictability, consistency, and efficiency.

Our expertise in process modelling, machine learning, and inline analytical technologies enables real-time insights, helping you optimise bioprocesses, minimise risks, and accelerate your path from lab-scale research to commercial-scale production. 

  • Oxford Biotrans
  • Calysta
  • Azotic
  • 3D Bio-Tissues
  • Newcastle University
  • Immune Boost Clinic

What we offer

Our specialised team apply advanced digital tools, real-time analytics, and AI-driven optimisation techniques, enhancing your bioprocess robustness, efficiency, and commercial viability. By leveraging these technologies, we significantly reduce risks associated with scale-up and accelerate your route to market.

What we offer

Our specialised team apply advanced digital tools, real-time analytics, and AI-driven optimisation techniques, enhancing your bioprocess robustness, efficiency, and commercial viability. By leveraging these technologies, we significantly reduce risks associated with scale-up and accelerate your route to market.

What we offer

Our specialised team apply advanced digital tools, real-time analytics, and AI-driven optimisation techniques, enhancing your bioprocess robustness, efficiency, and commercial viability. By leveraging these technologies, we significantly reduce risks associated with scale-up and accelerate your route to market.

Soft sensors and inline PAT for real-time process control

We integrate soft sensors and inline process analytical technology (PAT) to achieve continuous real-time monitoring and control, enhancing bioprocess consistency and quality. 

  • Real-time analytics to optimise process parameters and conditions. 

  • Continuous quality assurance and process validation. 

  • Improved product consistency and reduced batch variability. 

  • Integration of sensor data into comprehensive process control strategies. 

Soft sensors and inline PAT for real-time process control

We integrate soft sensors and inline process analytical technology (PAT) to achieve continuous real-time monitoring and control, enhancing bioprocess consistency and quality. 

  • Real-time analytics to optimise process parameters and conditions. 

  • Continuous quality assurance and process validation. 

  • Improved product consistency and reduced batch variability. 

  • Integration of sensor data into comprehensive process control strategies. 

Computational modelling and simulation

Our advanced computational modelling capabilities help you assess and optimise bioprocess scalability and performance, improving decision-making and resource efficiency. 

  • Computational Fluid Dynamics (CFD) for detailed process performance analysis. 

  • Multiphysics simulations for predictive bioprocess optimisation. 

  • Scale-down modelling to de-risk large-scale implementations. 

Computational modelling and simulation

Our advanced computational modelling capabilities help you assess and optimise bioprocess scalability and performance, improving decision-making and resource efficiency. 

  • Computational Fluid Dynamics (CFD) for detailed process performance analysis. 

  • Multiphysics simulations for predictive bioprocess optimisation. 

  • Scale-down modelling to de-risk large-scale implementations. 

Machine learning for bioprocess optimisation

Leveraging AI-driven machine learning methods, we optimise upstream and downstream bioprocess parameters, significantly enhancing yield, productivity, and economic viability. 

  • Predictive modelling of bioprocess parameters. 

  • Adaptive process control to minimise variability and optimise yields. 

  • Continuous process improvement through advanced data analytics. 

Machine learning for bioprocess optimisation

Leveraging AI-driven machine learning methods, we optimise upstream and downstream bioprocess parameters, significantly enhancing yield, productivity, and economic viability. 

  • Predictive modelling of bioprocess parameters. 

  • Adaptive process control to minimise variability and optimise yields. 

  • Continuous process improvement through advanced data analytics. 

Embedded Design of Experiments (DOE)

Our embedded DOE methodologies systematically optimise bioprocess conditions, ensuring robust, reproducible, and commercially viable outcomes. 

  • Systematic parameter optimisation to improve process efficiency. 

  • Reduction of experimental cost and time through intelligent experimental design. 

  • Enhanced process understanding and rapid decision-making. 

Embedded Design of Experiments (DOE)

Our embedded DOE methodologies systematically optimise bioprocess conditions, ensuring robust, reproducible, and commercially viable outcomes. 

  • Systematic parameter optimisation to improve process efficiency. 

  • Reduction of experimental cost and time through intelligent experimental design. 

  • Enhanced process understanding and rapid decision-making. 

Can’t find what you’re looking for?

With over 500 experts we are here to help.

Get in touch

Can’t find what you’re looking for?

With over 500 experts we are here to help.

Get in touch

Can’t find what you’re looking for?

With over 500 experts we are here to help.

Get in touch

Digitalisation and bioprocess optimisation applications

Our advanced digital and analytical techniques support a wide range of biotechnology applications.

Alternative proteins.

Nutraceutical production.

Sustainable chemical production.

Fermentation optimisation.

Agricultural biotechnology.

Bioproduct formulation.

3D computational fluid dynamics simulation showing coloured flow vectors around a mixing impeller.

Digitalisation and bioprocess optimisation applications

Our advanced digital and analytical techniques support a wide range of biotechnology applications.

Alternative proteins.

Nutraceutical production.

Sustainable chemical production.

Fermentation optimisation.

Agricultural biotechnology.

Bioproduct formulation.

3D computational fluid dynamics simulation showing coloured flow vectors around a mixing impeller.

Digitalisation and bioprocess optimisation applications

Our advanced digital and analytical techniques support a wide range of biotechnology applications.

Alternative proteins.

Nutraceutical production.

Sustainable chemical production.

Fermentation optimisation.

Agricultural biotechnology.

Bioproduct formulation.

3D computational fluid dynamics simulation showing coloured flow vectors around a mixing impeller.

How we support you

At CPI, we offer access to industry-relevant scale-up infrastructure and industry-experienced scientists and technologists, ensuring a smooth transition from early-stage development to commercial-scale manufacturing.

How we support you

At CPI, we offer access to industry-relevant scale-up infrastructure and industry-experienced scientists and technologists, ensuring a smooth transition from early-stage development to commercial-scale manufacturing.

How we support you

At CPI, we offer access to industry-relevant scale-up infrastructure and industry-experienced scientists and technologists, ensuring a smooth transition from early-stage development to commercial-scale manufacturing.

Optimise and de-risk your bioprocesses 

We help you navigate the complexities of bioprocess development, using advanced digitalisation tools to optimise performance and reduce variability. Our expertise spans from proof-of-concept to industrial production, ensuring your processes are scalable and commercially viable.

Optimise and de-risk your bioprocesses 

We help you navigate the complexities of bioprocess development, using advanced digitalisation tools to optimise performance and reduce variability. Our expertise spans from proof-of-concept to industrial production, ensuring your processes are scalable and commercially viable.

Scale with confidence 

Moving from lab-scale to full-scale production can be complex. We provide pilot and demonstration-scale facilities, enabling validation and refinement of your bioprocess using advanced computational modelling and techno-economic analyses, ensuring a smooth transition to commercial-scale production. 

Scale with confidence 

Moving from lab-scale to full-scale production can be complex. We provide pilot and demonstration-scale facilities, enabling validation and refinement of your bioprocess using advanced computational modelling and techno-economic analyses, ensuring a smooth transition to commercial-scale production. 

Intellectual property development and protection 

We support you in developing and securing your IP, providing an established environment for innovation. Our teams collaborate closely with you to protect your proprietary digitalisation and process optimisation techniques, maintaining your competitive advantage. 

Intellectual property development and protection 

We support you in developing and securing your IP, providing an established environment for innovation. Our teams collaborate closely with you to protect your proprietary digitalisation and process optimisation techniques, maintaining your competitive advantage. 

Navigate regulatory and commercial hurdles 

Our embedded DOE methodologies systematically optimise bioprocess conditions, ensuring robust, reproducible, and commercially viable outcomes. 

  • Systematic parameter optimisation to improve process efficiency. 

  • Reduction of experimental cost and time through intelligent experimental design. 

  • Enhanced process understanding and rapid decision-making. 

Navigate regulatory and commercial hurdles 

Our embedded DOE methodologies systematically optimise bioprocess conditions, ensuring robust, reproducible, and commercially viable outcomes. 

  • Systematic parameter optimisation to improve process efficiency. 

  • Reduction of experimental cost and time through intelligent experimental design. 

  • Enhanced process understanding and rapid decision-making. 

Facilitate investment and accelerate innovation 

Access to funding is critical for scaling innovations. We support you in securing public and private investment through strategic partnerships and grant applications, leveraging our extensive networks to drive your commercial success. By collaborating with industry, academia, and government, we provide essential resources, expertise, and market insights to accelerate your innovation journey. 

Facilitate investment and accelerate innovation 

Access to funding is critical for scaling innovations. We support you in securing public and private investment through strategic partnerships and grant applications, leveraging our extensive networks to drive your commercial success. By collaborating with industry, academia, and government, we provide essential resources, expertise, and market insights to accelerate your innovation journey. 

  • CPI scientist using an Olympus microscope with the magnified sample displayed on a monitor.
    Gloved scientist using a pipette to fill blue microplates at a laboratory bench.
  • Automated sampler probe dipping into a sample tube in a rack, with a CPI scientist watching behind.
    CPI scientist using a touchscreen control panel on a bioreactor system behind a glass screen.
  • Stainless steel pilot process rig with looped pipework and a blue pump in a facility.
  • CPI scientist working at a HEL parallel automated reactor system behind a glass door.
    CPI scientist drawing a process diagram on a glass screen in a laboratory.
  • Gloved hands holding a petri dish with a bacterial streak culture while using an inoculation tool.
    CPI scientist using an Olympus microscope with the magnified sample shown on a monitor.
  • Gloved hand holding a petri dish with orange bacterial colonies streaked across the agar.
  • CPI scientist using an Olympus microscope with the magnified sample displayed on a monitor.
    Gloved scientist using a pipette to fill blue microplates at a laboratory bench.
  • Automated sampler probe dipping into a sample tube in a rack, with a CPI scientist watching behind.
    CPI scientist using a touchscreen control panel on a bioreactor system behind a glass screen.
  • Stainless steel pilot process rig with looped pipework and a blue pump in a facility.
  • CPI scientist working at a HEL parallel automated reactor system behind a glass door.
    CPI scientist drawing a process diagram on a glass screen in a laboratory.
  • Gloved hands holding a petri dish with a bacterial streak culture while using an inoculation tool.
    CPI scientist using an Olympus microscope with the magnified sample shown on a monitor.
  • Gloved hand holding a petri dish with orange bacterial colonies streaked across the agar.
  • CPI scientist using an Olympus microscope with the magnified sample displayed on a monitor.
    Gloved scientist using a pipette to fill blue microplates at a laboratory bench.
  • Automated sampler probe dipping into a sample tube in a rack, with a CPI scientist watching behind.
    CPI scientist using a touchscreen control panel on a bioreactor system behind a glass screen.
  • Stainless steel pilot process rig with looped pipework and a blue pump in a facility.
  • CPI scientist working at a HEL parallel automated reactor system behind a glass door.
    CPI scientist drawing a process diagram on a glass screen in a laboratory.
  • Gloved hands holding a petri dish with a bacterial streak culture while using an inoculation tool.
    CPI scientist using an Olympus microscope with the magnified sample shown on a monitor.
  • Gloved hand holding a petri dish with orange bacterial colonies streaked across the agar.
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Trusted by leading organisations

Showing slide 1 of 1
Oxford Biotrans

Our project with CPI was the springboard for our technology commercialisation programme and subsequent market launch. The CPI team were knowledgeable, approachable and responsive and proved invaluable in rapidly overcoming the complex challenges that developing any new process requires.

A headshot of Jason King. .

Jason King

CEO

Touchlight Genetics

CPI has skillsets and equipment that are not readily available anywhere else. By using CPI’s skills, we have saved many months of process development.

Headshot of Dr Jill Makin, CTO

Dr Jill Makin

CTO

Calysta

We chose Teesside as a preferred location due to the commercial attractiveness, technical skills and research and development expertise in the area.

Headshot of Alan Shaw, CEO

Alan Shaw

CEO

Trusted by leading organisations

Showing slide 1 of 1
Oxford Biotrans

Our project with CPI was the springboard for our technology commercialisation programme and subsequent market launch. The CPI team were knowledgeable, approachable and responsive and proved invaluable in rapidly overcoming the complex challenges that developing any new process requires.

A headshot of Jason King. .

Jason King

CEO

Touchlight Genetics

CPI has skillsets and equipment that are not readily available anywhere else. By using CPI’s skills, we have saved many months of process development.

Headshot of Dr Jill Makin, CTO

Dr Jill Makin

CTO

Calysta

We chose Teesside as a preferred location due to the commercial attractiveness, technical skills and research and development expertise in the area.

Headshot of Alan Shaw, CEO

Alan Shaw

CEO

Trusted by leading organisations

Showing slide 1 of 1
Oxford Biotrans

Our project with CPI was the springboard for our technology commercialisation programme and subsequent market launch. The CPI team were knowledgeable, approachable and responsive and proved invaluable in rapidly overcoming the complex challenges that developing any new process requires.

A headshot of Jason King. .

Jason King

CEO

Touchlight Genetics

CPI has skillsets and equipment that are not readily available anywhere else. By using CPI’s skills, we have saved many months of process development.

Headshot of Dr Jill Makin, CTO

Dr Jill Makin

CTO

Calysta

We chose Teesside as a preferred location due to the commercial attractiveness, technical skills and research and development expertise in the area.

Headshot of Alan Shaw, CEO

Alan Shaw

CEO

Why choose CPI?

Work with us to defer capital and workforce investments until your product or process is proven at scale.

Real-time insights

Advanced inline sensors and process analytical technologies (PAT).

Predictive modelling

State-of-the-art computational simulations ensuring robust scalability.

AI-driven optimisation

Machine learning for systematic enhancement of bioprocess performance.

Robust scale-up

Digital twins and modelling tools that reduce variability during scale-up.

Embedded design of experiments

Systematic experimental design accelerating process refinement.

Strong industry networks

Strategic partnerships enhancing innovation speed and market integration.

Why choose CPI?

Work with us to defer capital and workforce investments until your product or process is proven at scale.

Real-time insights

Advanced inline sensors and process analytical technologies (PAT).

Predictive modelling

State-of-the-art computational simulations ensuring robust scalability.

AI-driven optimisation

Machine learning for systematic enhancement of bioprocess performance.

Robust scale-up

Digital twins and modelling tools that reduce variability during scale-up.

Embedded design of experiments

Systematic experimental design accelerating process refinement.

Strong industry networks

Strategic partnerships enhancing innovation speed and market integration.

Why choose CPI?

Work with us to defer capital and workforce investments until your product or process is proven at scale.

Real-time insights

Advanced inline sensors and process analytical technologies (PAT).

Predictive modelling

State-of-the-art computational simulations ensuring robust scalability.

AI-driven optimisation

Machine learning for systematic enhancement of bioprocess performance.

Robust scale-up

Digital twins and modelling tools that reduce variability during scale-up.

Embedded design of experiments

Systematic experimental design accelerating process refinement.

Strong industry networks

Strategic partnerships enhancing innovation speed and market integration.

Get in touch

Get in touch

Get in touch

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