Bioprocess development and scale-up

Microorganisms, animal cells, and plant cells

Tailored microbial strain selection, characterisation, engineering and adaption to unlock bioprocess efficiency and commercial viability.

Get in touch

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From discovery to industrial scale

Harnessing the full potential of microorganisms is critical for sustainable, efficient, and cost-effective bioprocesses. At CPI, we leverage our extensive microbial expertise and advanced facilities to help you optimise strain selection, performance, and scalability, significantly reducing your journey from initial research to market-ready production. 

Our integrated approach ensures microorganisms deliver maximum productivity and consistency, enabling successful industrial-scale implementation for diverse applications, from food ingredients and therapeutics to sustainable chemicals and agricultural solutions. 

CPI expert looking through a microscope.

Bioprocess development and scale-up

Microorganisms, animal cells, and plant cells

Tailored microbial strain selection, characterisation, engineering and adaption to unlock bioprocess efficiency and commercial viability.

Get in touch

View capabilities

From discovery to industrial scale

Harnessing the full potential of microorganisms is critical for sustainable, efficient, and cost-effective bioprocesses. At CPI, we leverage our extensive microbial expertise and advanced facilities to help you optimise strain selection, performance, and scalability, significantly reducing your journey from initial research to market-ready production. 

Our integrated approach ensures microorganisms deliver maximum productivity and consistency, enabling successful industrial-scale implementation for diverse applications, from food ingredients and therapeutics to sustainable chemicals and agricultural solutions. 

CPI expert looking through a microscope.

Bioprocess development and scale-up

Microorganisms, animal cells, and plant cells

Tailored microbial strain selection, characterisation, engineering and adaption to unlock bioprocess efficiency and commercial viability.

Get in touch

View capabilities

From discovery to industrial scale

Harnessing the full potential of microorganisms is critical for sustainable, efficient, and cost-effective bioprocesses. At CPI, we leverage our extensive microbial expertise and advanced facilities to help you optimise strain selection, performance, and scalability, significantly reducing your journey from initial research to market-ready production. 

Our integrated approach ensures microorganisms deliver maximum productivity and consistency, enabling successful industrial-scale implementation for diverse applications, from food ingredients and therapeutics to sustainable chemicals and agricultural solutions. 

  • Oxford Biotrans
  • Calysta
  • Azotic
  • 3D Bio-Tissues
  • Newcastle University
  • Immune Boost Clinic

What we offer

CPI offers expertise in robust and scalable microbial strain development, selection, characterisation, and optimisation. Our dedicated host strain development team supports the optimisation and development of bacteria, yeast, filamentous fungi, microalgae, plant and animal cells to enhance the efficiency and economic viability of bioprocesses.

What we offer

CPI offers expertise in robust and scalable microbial strain development, selection, characterisation, and optimisation. Our dedicated host strain development team supports the optimisation and development of bacteria, yeast, filamentous fungi, microalgae, plant and animal cells to enhance the efficiency and economic viability of bioprocesses.

What we offer

CPI offers expertise in robust and scalable microbial strain development, selection, characterisation, and optimisation. Our dedicated host strain development team supports the optimisation and development of bacteria, yeast, filamentous fungi, microalgae, plant and animal cells to enhance the efficiency and economic viability of bioprocesses.

Strain characterisation

We identify, screen, and select microbial strains tailored specifically for your commercial applications, ensuring rapid progress from discovery to development. 

  • High-throughput screening platforms for rapid strain selection. 

  • Characterisation of strain robustness and suitability. 

  • Early-stage feasibility studies to quickly assess commercial potential. 

  • Strain bank management and storage for ongoing research and development 

  • With an expert biosafety team, robust safety management processes, and containment level 1 and 2 facilities we can handle your microbial needs including GMMOs. 

  • Rapid identification of suitable strains through our collaborative academic network. 

  • Detailed strain characterisation including growth kinetics, stability studies, and performance under variable conditions. 

Strain characterisation

We identify, screen, and select microbial strains tailored specifically for your commercial applications, ensuring rapid progress from discovery to development. 

  • High-throughput screening platforms for rapid strain selection. 

  • Characterisation of strain robustness and suitability. 

  • Early-stage feasibility studies to quickly assess commercial potential. 

  • Strain bank management and storage for ongoing research and development 

  • With an expert biosafety team, robust safety management processes, and containment level 1 and 2 facilities we can handle your microbial needs including GMMOs. 

  • Rapid identification of suitable strains through our collaborative academic network. 

  • Detailed strain characterisation including growth kinetics, stability studies, and performance under variable conditions. 

High-throughput screening

Our automated platforms facilitate the rapid selection and optimisation of strains, significantly reducing development timelines and improving data reliability. 

  • Accelerated strain characterisation and productivity analysis. 

  • High-quality data generation for strain robustness and scalability. 

  • Optimisation of growth parameters and nutrient utilisation. 

  • Parallel experimentation capabilities to increase experimental throughput. 

  • Integration with advanced analytics for real-time data capture and process insights. 

High-throughput screening

Our automated platforms facilitate the rapid selection and optimisation of strains, significantly reducing development timelines and improving data reliability. 

  • Accelerated strain characterisation and productivity analysis. 

  • High-quality data generation for strain robustness and scalability. 

  • Optimisation of growth parameters and nutrient utilisation. 

  • Parallel experimentation capabilities to increase experimental throughput. 

  • Integration with advanced analytics for real-time data capture and process insights. 

Microbial strain engineering

We develop both genetically modified (GM) and non-GM microbial strains, tailored specifically to your bioprocess requirements, enhancing strain productivity and commercial viability. 

  • Strain engineering for recombinant protein production. 

  • Metabolic pathway engineering for enhanced productivity and yield. 

  • Non-GM optimisation strategies for improved efficiency and reduced cost. 

  • Regulatory guidance for compliance (GMO and non-GMO strains). 

  • Targeted genetic modifications to improve substrate utilisation and product specificity. 

  • Robust host strain development to ensure process stability at scale. 

Microbial strain engineering

We develop both genetically modified (GM) and non-GM microbial strains, tailored specifically to your bioprocess requirements, enhancing strain productivity and commercial viability. 

  • Strain engineering for recombinant protein production. 

  • Metabolic pathway engineering for enhanced productivity and yield. 

  • Non-GM optimisation strategies for improved efficiency and reduced cost. 

  • Regulatory guidance for compliance (GMO and non-GMO strains). 

  • Targeted genetic modifications to improve substrate utilisation and product specificity. 

  • Robust host strain development to ensure process stability at scale. 

Strain optimisation and validation

We ensure robust, scalable microbial strains through comprehensive validation and optimisation processes, preparing your microorganisms for seamless scale-up and commercial deployment. 

  • Bespoke infrastructure for rapid proof-of-concept and scale-down studies. 

  • Integration of upstream process development with scale-up capabilities. 

  • Access to pilot-scale infrastructure for industrially relevant validation. 

Strain optimisation and validation

We ensure robust, scalable microbial strains through comprehensive validation and optimisation processes, preparing your microorganisms for seamless scale-up and commercial deployment. 

  • Bespoke infrastructure for rapid proof-of-concept and scale-down studies. 

  • Integration of upstream process development with scale-up capabilities. 

  • Access to pilot-scale infrastructure for industrially relevant validation. 

Can’t find what you’re looking for?

With over 500 experts we are here to help.

Get in touch

Can’t find what you’re looking for?

With over 500 experts we are here to help.

Get in touch

Can’t find what you’re looking for?

With over 500 experts we are here to help.

Get in touch

Microorganisms, animal and plant cells applications

We support various sectors by developing robust microbial strains optimised for efficient and scalable commercial applications:

Alternative proteins.

Nutraceuticals.

Probiotics and prebiotics.

Enzyme production.

Sustainable chemicals and materials.

Biobased monomers and polymers.

Alternative routes to petrochemical based products.

Biopesticides, biostimulants and biofertilisers.

Green-gloved hands loading amber sample vials into a blue rack of a laboratory analyser.

Microorganisms, animal and plant cells applications

We support various sectors by developing robust microbial strains optimised for efficient and scalable commercial applications:

Alternative proteins.

Nutraceuticals.

Probiotics and prebiotics.

Enzyme production.

Sustainable chemicals and materials.

Biobased monomers and polymers.

Alternative routes to petrochemical based products.

Biopesticides, biostimulants and biofertilisers.

Green-gloved hands loading amber sample vials into a blue rack of a laboratory analyser.

Microorganisms, animal and plant cells applications

We support various sectors by developing robust microbial strains optimised for efficient and scalable commercial applications:

Alternative proteins.

Nutraceuticals.

Probiotics and prebiotics.

Enzyme production.

Sustainable chemicals and materials.

Biobased monomers and polymers.

Alternative routes to petrochemical based products.

Biopesticides, biostimulants and biofertilisers.

Green-gloved hands loading amber sample vials into a blue rack of a laboratory analyser.

How we support you

We provide end-to-end support to help you optimise microbial strains and accelerate the commercialisation of your bioprocess innovations. Our experienced team and tailored infrastructure enable you to rapidly and reliably develop robust, commercially viable microorganisms.

How we support you

We provide end-to-end support to help you optimise microbial strains and accelerate the commercialisation of your bioprocess innovations. Our experienced team and tailored infrastructure enable you to rapidly and reliably develop robust, commercially viable microorganisms.

How we support you

We provide end-to-end support to help you optimise microbial strains and accelerate the commercialisation of your bioprocess innovations. Our experienced team and tailored infrastructure enable you to rapidly and reliably develop robust, commercially viable microorganisms.

Optimise and de-risk your microbial development

We help you overcome the complexities of microbial strain optimisation, ensuring your strains are robust, productive, and scalable. Our expertise supports your journey from early strain selection to validated, commercial-scale microbial production. 

Optimise and de-risk your microbial development

We help you overcome the complexities of microbial strain optimisation, ensuring your strains are robust, productive, and scalable. Our expertise supports your journey from early strain selection to validated, commercial-scale microbial production. 

Scale microbial processes confidently 

Scaling microbial processes from laboratory to commercial-scale production is challenging. Our state-of-the-art facilities enable you to validate strain performance and refine process parameters, ensuring a smooth and confident transition to industrial-scale manufacturing. 

Scale microbial processes confidently 

Scaling microbial processes from laboratory to commercial-scale production is challenging. Our state-of-the-art facilities enable you to validate strain performance and refine process parameters, ensuring a smooth and confident transition to industrial-scale manufacturing. 

Develop and protect intellectual property

We help you develop and secure your intellectual property by providing expert guidance and a secure innovation environment. Our team collaborates closely with you to ensure your microbial innovations are effectively protected and commercially viable. 

Develop and protect intellectual property

We help you develop and secure your intellectual property by providing expert guidance and a secure innovation environment. Our team collaborates closely with you to ensure your microbial innovations are effectively protected and commercially viable. 

Navigate regulatory pathways effectively 

We ensure robust, scalable microbial strains through comprehensive validation and optimisation processes, preparing your microorganisms for seamless scale-up and commercial deployment. 

  • Bespoke infrastructure for rapid proof-of-concept and scale-down studies. 

  • Integration of upstream process development with scale-up capabilities. 

  • Access to pilot-scale infrastructure for industrially relevant validation. 

Navigate regulatory pathways effectively 

We ensure robust, scalable microbial strains through comprehensive validation and optimisation processes, preparing your microorganisms for seamless scale-up and commercial deployment. 

  • Bespoke infrastructure for rapid proof-of-concept and scale-down studies. 

  • Integration of upstream process development with scale-up capabilities. 

  • Access to pilot-scale infrastructure for industrially relevant validation. 

Facilitate investment and accelerate microbial innovation 

Access to funding and strategic partnerships is critical for successful commercialisation. We assist you in securing public and private investment, guiding you through grant applications and funding rounds. Our collaborative network provides you with essential resources, insights, and market expertise to accelerate your microbial innovation journey. 

Facilitate investment and accelerate microbial innovation 

Access to funding and strategic partnerships is critical for successful commercialisation. We assist you in securing public and private investment, guiding you through grant applications and funding rounds. Our collaborative network provides you with essential resources, insights, and market expertise to accelerate your microbial innovation journey. 

Access our collaborative academic network 

We leverage our extensive network of UK and international academic partners to rapidly identify and introduce you to institutions with specialised tools and processes. This collaboration can significantly augment your chosen host strain, providing quick and effective integration of complementary expertise into your microbial development programme. 

Access our collaborative academic network 

We leverage our extensive network of UK and international academic partners to rapidly identify and introduce you to institutions with specialised tools and processes. This collaboration can significantly augment your chosen host strain, providing quick and effective integration of complementary expertise into your microbial development programme. 

  • CPI scientist using a VWR pipette controller to fill a serological pipette in a laboratory.
    Gloved scientist using a pipette to fill blue microplates at a laboratory bench.
  • Automated sampler probe dipping into a sample tube in a rack, with a CPI scientist watching behind.
    CPI scientist operating an ambr 250 automated bioreactor system with a tablet.
  • Stainless steel pilot process rig with looped pipework and a blue pump in a facility.
  • CPI scientist working at a HEL parallel automated reactor system behind a glass door.
    CPI scientist drawing a process diagram on a glass screen in a laboratory.
  • Gloved hands holding a petri dish with a bacterial streak culture while using an inoculation tool.
    CPI scientist using an Olympus microscope with the magnified sample shown on a monitor.
  • Gloved hand holding a petri dish with orange bacterial colonies streaked across the agar.
  • CPI scientist using a VWR pipette controller to fill a serological pipette in a laboratory.
    Gloved scientist using a pipette to fill blue microplates at a laboratory bench.
  • Automated sampler probe dipping into a sample tube in a rack, with a CPI scientist watching behind.
    CPI scientist operating an ambr 250 automated bioreactor system with a tablet.
  • Stainless steel pilot process rig with looped pipework and a blue pump in a facility.
  • CPI scientist working at a HEL parallel automated reactor system behind a glass door.
    CPI scientist drawing a process diagram on a glass screen in a laboratory.
  • Gloved hands holding a petri dish with a bacterial streak culture while using an inoculation tool.
    CPI scientist using an Olympus microscope with the magnified sample shown on a monitor.
  • Gloved hand holding a petri dish with orange bacterial colonies streaked across the agar.
  • CPI scientist using a VWR pipette controller to fill a serological pipette in a laboratory.
    Gloved scientist using a pipette to fill blue microplates at a laboratory bench.
  • Automated sampler probe dipping into a sample tube in a rack, with a CPI scientist watching behind.
    CPI scientist operating an ambr 250 automated bioreactor system with a tablet.
  • Stainless steel pilot process rig with looped pipework and a blue pump in a facility.
  • CPI scientist working at a HEL parallel automated reactor system behind a glass door.
    CPI scientist drawing a process diagram on a glass screen in a laboratory.
  • Gloved hands holding a petri dish with a bacterial streak culture while using an inoculation tool.
    CPI scientist using an Olympus microscope with the magnified sample shown on a monitor.
  • Gloved hand holding a petri dish with orange bacterial colonies streaked across the agar.
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Trusted by leading organisations

Showing slide 1 of 1
Oxford Biotrans

Our project with CPI was the springboard for our technology commercialisation programme and subsequent market launch. The CPI team were knowledgeable, approachable and responsive and proved invaluable in rapidly overcoming the complex challenges that developing any new process requires.

A headshot of Jason King. .

Jason King

CEO

Touchlight Genetics

CPI has skillsets and equipment that are not readily available anywhere else. By using CPI’s skills, we have saved many months of process development.

Headshot of Dr Jill Makin, CTO

Dr Jill Makin

CTO

Calysta

We chose Teesside as a preferred location due to the commercial attractiveness, technical skills and research and development expertise in the area.

Headshot of Alan Shaw, CEO

Alan Shaw

CEO

Trusted by leading organisations

Showing slide 1 of 1
Oxford Biotrans

Our project with CPI was the springboard for our technology commercialisation programme and subsequent market launch. The CPI team were knowledgeable, approachable and responsive and proved invaluable in rapidly overcoming the complex challenges that developing any new process requires.

A headshot of Jason King. .

Jason King

CEO

Touchlight Genetics

CPI has skillsets and equipment that are not readily available anywhere else. By using CPI’s skills, we have saved many months of process development.

Headshot of Dr Jill Makin, CTO

Dr Jill Makin

CTO

Calysta

We chose Teesside as a preferred location due to the commercial attractiveness, technical skills and research and development expertise in the area.

Headshot of Alan Shaw, CEO

Alan Shaw

CEO

Trusted by leading organisations

Showing slide 1 of 1
Oxford Biotrans

Our project with CPI was the springboard for our technology commercialisation programme and subsequent market launch. The CPI team were knowledgeable, approachable and responsive and proved invaluable in rapidly overcoming the complex challenges that developing any new process requires.

A headshot of Jason King. .

Jason King

CEO

Touchlight Genetics

CPI has skillsets and equipment that are not readily available anywhere else. By using CPI’s skills, we have saved many months of process development.

Headshot of Dr Jill Makin, CTO

Dr Jill Makin

CTO

Calysta

We chose Teesside as a preferred location due to the commercial attractiveness, technical skills and research and development expertise in the area.

Headshot of Alan Shaw, CEO

Alan Shaw

CEO

Why choose CPI?

Work with us to defer capital and workforce investments until your product or process is proven at scale.

Specialist strain development

Tailored microbial optimisation and strain validation.

Accelerated development

High-throughput screening for rapid strain selection.

Flexible solutions

Expertise in both microbial and non-microbial host systems.

Collaborative networks

Strong academic links for complementary strain enhancement tools.

Regulatory expertise

Comprehensive support in meeting global bioprocess standards.

Commercial scalability

Seamless transition from proof-of-concept to commercial-scale applications.

Why choose CPI?

Work with us to defer capital and workforce investments until your product or process is proven at scale.

Specialist strain development

Tailored microbial optimisation and strain validation.

Accelerated development

High-throughput screening for rapid strain selection.

Flexible solutions

Expertise in both microbial and non-microbial host systems.

Collaborative networks

Strong academic links for complementary strain enhancement tools.

Regulatory expertise

Comprehensive support in meeting global bioprocess standards.

Commercial scalability

Seamless transition from proof-of-concept to commercial-scale applications.

Why choose CPI?

Work with us to defer capital and workforce investments until your product or process is proven at scale.

Specialist strain development

Tailored microbial optimisation and strain validation.

Accelerated development

High-throughput screening for rapid strain selection.

Flexible solutions

Expertise in both microbial and non-microbial host systems.

Collaborative networks

Strong academic links for complementary strain enhancement tools.

Regulatory expertise

Comprehensive support in meeting global bioprocess standards.

Commercial scalability

Seamless transition from proof-of-concept to commercial-scale applications.

Get in touch

Get in touch

Get in touch

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