Ventus Medical
Developing a nicotine replacement therapy
Bringing a novel pharmaceutical electronic nicotine delivery system to clinical trial
CPI is working with Ventus Medical, a pharmaceutical company specialising in the innovation of novel inhalation technologies. Ventus Medical is creating a nicotine replacement therapy that has been designed to help adult smokers to quit smoking by alleviating nicotine withdrawal symptoms.
Ventus Medical is addressing one of the greatest public health challenges by realising safe and effective tools that can be deployed by policymakers to reduce morbidity and mortality and improve the lives of the general population.
We are working with Ventus Medical to help design and create a replaceable single-use cartridge that will deliver an accurate nicotine dosage to adult smokers whilst eliminating toxicant exposure, which in turn will reduce cravings and alleviate nicotine withdrawal symptoms.
![](https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/ventus-case-study-02.jpg?w=1920&h=1080&q=60&fm=jpg&fit=crop&dm=1630417902&s=e2a36665ba2b832332b6d3f9f31538b5 1920w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/ventus-case-study-02.jpg?w=1120&h=630&q=60&fm=jpg&fit=crop&dm=1630417902&s=7f6e4782ad1d1e93151cc5fb2300b927 1120w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/ventus-case-study-02.jpg?w=800&h=450&q=60&fm=jpg&fit=crop&dm=1630417902&s=3fccdda15b0715b351b8f19c0d749e94 800w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/ventus-case-study-02.jpg?w=1600&h=900&q=45&fm=jpg&fit=crop&dm=1630417902&s=7b72ece98ae1d35c662077a48b032f22 1600w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/ventus-case-study-02.jpg?w=480&h=270&q=60&fm=jpg&fit=crop&dm=1630417902&s=d1d2fbab5d47fb0d9a03f55076bc6f17 480w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/ventus-case-study-02.jpg?w=960&h=540&q=45&fm=jpg&fit=crop&dm=1630417902&s=4c7d8bd46387a2945e0aff7f0533b66f 960w)
“ CPI has played a pivotal role in the development of ENHALE, allowing us to identify the optimum materials and processes for the scalable & sustainable manufacturer of a safe and efficacious medicine. ”
![David Lawson David Lawson](https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/david-lawson-small.jpg?w=100&h=100&q=60&fm=jpg&fit=crop&dm=1630401819&s=56d73bfbeaec53eefe1b88a199d1a0f7)
Partners
Achievements
Inputs
- Technical expertise
- Access to state-of-the-art equipment
- Proof of concept
- Initial product development
Outputs
- Development of a new product
- De-risking the costs involved in product development
- Reduce time to market
Outcomes
- Validation of technology
- New product for the market
- Reducing design/manufacturing cost
![](https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/ventus-case-study-03.jpg?w=1920&h=1080&q=60&fm=jpg&fit=crop&dm=1630417850&s=29a52b2975b4b5d1757f5e26aebbc1a5 1920w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/ventus-case-study-03.jpg?w=1120&h=630&q=60&fm=jpg&fit=crop&dm=1630417850&s=a9b565f0f790a1f3cdbd521859a99a22 1120w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/ventus-case-study-03.jpg?w=800&h=450&q=60&fm=jpg&fit=crop&dm=1630417850&s=02da2fa859b5aaae18e2bff6e9ca0a38 800w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/ventus-case-study-03.jpg?w=1600&h=900&q=45&fm=jpg&fit=crop&dm=1630417850&s=d15ca4d62a7c52f92c743aeaf8f6a5dd 1600w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/ventus-case-study-03.jpg?w=480&h=270&q=60&fm=jpg&fit=crop&dm=1630417850&s=20c0056d7211d70be0953699a3bc6a0b 480w, https://optimise2.assets-servd.host/smart-hoopoe/production/content/images/ventus-case-study-03.jpg?w=960&h=540&q=45&fm=jpg&fit=crop&dm=1630417850&s=c0e60abd564e91bf96fbac9d939d0428 960w)
The challenge
Ventus Medical is addressing one of the greatest public health challenges by realising safe and effective tools that can be deployed by policymakers to reduce morbidity and mortality and improve the lives of the general population.
We are working with Ventus Medical to help design and create a replaceable single-use cartridge that will deliver an accurate nicotine dosage to adult smokers whilst eliminating toxicant exposure, which in turn will reduce cravings and alleviate nicotine withdrawal symptoms.
How CPI helped
CPI has been engaged to develop an innovative heating element within the cartridge that aerosolises the formulation so that it can be inhaled by the user during use. An iterative design and optimisation process was employed to assess different designs and materials to develop a reproducible device that operated within the target range. The cartridges had to be produced to specification and at scale to ensure readiness for a clinical trial which is scheduled for 2021.
Working together, CPI has assisted in reducing overall development time and expediting time to market through rapid development of design and manufacturing practices required to deliver this innovative product. CPI has reduced costs, increased margins and reduced the time to clinic through the delivery of specialist skills and facilities within the flexible electronics market and medical devices.
CPI’s blend of practical and theoretical experience has helped Ventus Medical to develop its medical device product quickly and provided options on the manufacturing processes at scale. Proof of concepts that support sustainability are critical consideration of the design process and the exploration of different materials is part of the reported outcomes that CPI can deliver to clients.
As either a direct client or through a channel, CPI can help deliver an outcome that is underpinned by scientific expertise, reduces time to market and eliminates unnecessary manufacturing costs.
Related
Technologies
Markets
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