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Supporting UK biologics companies with funding and technology access

Supporting the UK’s biologics businesses with access to finance, multi-drug modality process enhancement and advanced analytics.

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Supporting the UK’s bioscience industry progression towards investment and the clinic

Access to technical expertise, funding and innovation consultancy to continue and support your development.

CPI helps bioscience companies move along the developmental pathway with our unique approach, expertise and experience.


BioPharam Lab

Why work with us?

  • Multi-Modality Pipeline Progression: Support with a broad spectrum of pipelines including antibodies, therapeutic proteins, vaccines, viral vectors and small molecules
  • Drug Delivery Solutions: Ranging from nanomedicine encapsulation through to conjugation services to increase drug targeting and stability for improved pharmacokinetics
  • Enhancing Industry Processing: Increase process speed, robustness and reliability by developing new and emerging drug manufacturing technologies at all process stages across multiple expression systems
  • Advancing Molecule, Process and Supply Chain Insight: CPI’s analytical offering ranges from nano-scale molecule configuration through to intercontinental supply chain tracking enabled by smart pharmaceutical packaging
  • Experts in Securing Finance: Our in-house bid managers can translate the complex funding environment into a suitable route for your company’s progress. The team support you in identifying the most appropriate funding source, navigating the application process, and drawing on their expertise to ensure you have the best chance in securing essential funding.

How to work with us

Fee for Service

These follow a more traditional model, through bespoke work packages to address your needs and requirements. Projects can range from utilising our unique expertise through consultancy and technical support, to extensive process development and optimisation programmes with supporting analytics.

Downstream

Collaborative Research and Development

These CR&D programmes draw on a range of public funding options such as Innovate UK or Horizon 2020 providing non-diluting funding for your needs. Our specialised bid managers will assist you to identify partners, build consortia and navigate the complex funding landscape to find the right funding for your project.

Collaboration in BioPharma

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Extensive knowledge and support for your field

Are you a drug developer?

  • Multi-drug modality handling capability including therapeutic proteins, vaccines, nanomedicines, small molecules and viral vectors for pipeline progression.
  • Build in process scalability and process understanding to reduce or remove costly scaling issues as your drug progresses along the clinical pathway.
  • Benefit from independent data generation for clinical partnering or investor pitching, technical and market evaluation to support investment rounds and process data for pre-clinical progression towards IND submission and clinical trials.
  • Work with our research and development team to increase capital efficiency and decrease risk along the developmental pathway

Are you a product or equipment developer/vendor?

  • Provide an integrated lab-based independent technology evaluation and cost of goods consultancy to aid your product’s development.
  • Facilitate introduction to key partners along the supply chain with the potential for joint technology development projects.
  • Benefit from independent data generation for partner or investor pitching.
  • Independently evaluate your technology for investment or partnering proposals, and carry out market scoping and cost of goods analysis.

Our state-of-the-art facilities and expertise

  • Upstream Processing Capability

    Upstream Processing Capability

    Our suite of next generation high throughput technologies will rapidly determine the optimal parameters for upscaling your process. One of the many examples is the ambr® 250 bioreactor system, which:

    • Is suitable for mammalian and microbial processes
    • Provides a body of evidence for presentation to investors and regulators to support your process development pathway
    • Minimises the total number of experiments typically required for process development, with the associated cost savings, while generating more comprehensive data sets.
    ambr® 250 bioreactor
    ambr® 250 bioreactor
  • Downstream Processing Capability

    Downstream Processing Capability

    • Perkin Elmer Janus liquid handling robot – Rapid, high throughput data generation for downstream resin screening, with CPI’s ability to screen a high number of resins ensuring a higher likelihood of process efficient and economically viable resin choice.
    • Novasep BioSC – A next generation simulated moving bed chromatography system capable of running continuous chromatography processes to compare batch and continuous processing options for your drug, with the potential to deliver significant cost savings versus batch processes.
    • GE AKTA Avant 150 – Rapid, high throughput and scalable data generation.
    • Including fill finish and lyophilisation
    Perkin Elmer Janus liquid handling robot
    Perkin Elmer Janus liquid handling robot
  • Advanced Analytical Capability

    Advanced Analytical Capability

    CPI has advanced analytical capability to provide enhanced process insights and bespoke analytical development programmes. CPI can offer access to:

    • Intact and subunit mass
    • Peptide mapping
    • N-Glycan profiling
    • Site specific modifications (e.g. oxidation and deamidation)
    • Charge variant profiling
    • Aggregation profiling
    • Melting point (Tm) determination
    • Characterisation of secondary structure
    • Higher order structure characterisation using hydrogen deuterium exchange with mass spectrometry
    CPI's advanced Analytical Capability
    CPI's advanced Analytical Capability
ambr® 250 bioreactor
Advanced Analytical Capability
Downstream Processing

Find out how we can help you

Contact Us Today