Scientist 1 — Microbial Downstream

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Job Details

Darlington, England
£26,000 - £34,000 per annum - dependent on experience
Full-time - Permanent
Science and Engineering
03 Jun 2024 - 23:45
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About CPI

CPI helps make great ideas and inventions a reality. We’re a team of intelligent people using advances in science and technology to solve the biggest global challenges in healthcare and sustainability.

Through our incredible people and innovation infrastructure, we collaborate with our partners in industry, academia, government, and the investment community to accelerate the development and commercialisation of innovative products.

From health technologies and pharmaceuticals to sustainable food and materials innovations, we turn the entrepreneurial spirit and radical thinking of our people and partners into incredible impact that makes our world a better place.

Why this role is important for CPI’s work

CPI is recruiting for a Microbial Downstream Scientist to join the established Microbial downstream team, based at the National Biologics Manufacturing Centre in Darlington.

The Downstream Process team assists companies with purification strategies for Biotherapeutics, working with a diverse range of modalities including recombinant proteins, antibodies, AAVs and RNA. The team are involved in a variety of scales from high-throughput, small-scale screening through to process scale-up and demonstration. 

Reporting to the Team, Leader – Downstream Process, the role of Scientist – Downstream involves developing and applying knowledge/​expertise relevant to downstream processing of biopharmaceuticals such as proteins, viral vectors, and nucleic-acid based products expressed in mammalian, bacterial, insect, yeast cells and/​or cell-free systems. You will have the opportunity to work across a variety of product types and process scales with opportunities for networking across other business units within CPI and supporting a diverse set of people.

Key tasks in the Scientist role will include (but are not limited to the below), please download the job description for full details available on the CPI careers page:

  • To keep self up to date with developments in areas relevant to role, and/​or legislative and SHE related changes as communicated by senior colleagues, ensuring understanding of these and any associated new best practice, methods, or techniques. 
  • To present and formally report experimental conclusions and supporting data for internal peer review and submission to clients, to agreed timescales and standards.
  • To actively engage in hazard studies / SRA studies and discussions, as appropriate to role level. 
  • To set up, plan and execute experimental / pilot scale runs and analyse, interpret, and report the results of these within agreed timescales and quality standards, and in accordance with project / client requirements. 
  • To be responsible for providing clearly documented records of technical data, decisions, methodologies, calculations, and software use in an agreed format.
  • To take ownership in agreeing weekly workplans with line manager, project manager(s) and other relevant stakeholders, and delivering plan to agreed schedule.
  • To be responsible for the maintenance and calibration of equipment to ensure it operates in a safe and efficient manner and is available to meet customer needs.

The person we are seeking


  • Educated to HNC or Foundation Degree level (or equivalent) in a Scientific/​Engineering discipline plus relevant industrial experience OR Educated to Degree level (or equivalent) in a Scientific/​Engineering discipline
  • A foundation of technical knowledge and some underpinning knowledge of downstream processing, as well as evidence of technical problem solving gained in academic or industrial environments

It would be great if you also had:

  • Chartered status with a relevant professional institution

What does CPI offer you?

At CPI, we offer a wide range of benefits to our employees, this includes:

  • Up to 36 days holiday, including bank holidays – Plus a holiday purchasing scheme
  • Generous pension scheme
  • Life assurance and accident insurance schemes
  • Flexible working
  • Learning and Development Opportunities
  • Free parking

Find out more about our culture and benefits.

Additional information

CPI is an organisation based in the UK. Commencement of employment is conditional to demonstrating right to work in the UK, sponsorship may be available.

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