We are continuing to work with and deliver for our partners during the COVID-19 pandemic. Read our full response for more details.

Downstream Process Development Scientist

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Job Details

Location
Darlington
Salary
£25,000 - £60,000 per annum, depending on experience
Employment
Full-time - Permanent Full-time - Fixed term
Team
Science and Engineering
Deadline
05 Jul 2020 - 23:30
Reference
CPI-782-20
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CPI in a nutshell

At CPI we work with our partners to translate inventions into products and processes that enhance health and well-being, protect and improve our environment and increase productivity across industries.

With a deep understanding of innovation processes and funding, outstanding technical expertise and industry relevant assets, we enable products and processes to be quickly and cost-effectively brought to market. This supports the development of next-generation manufacturing, highly-skilled jobs and economic growth for the UK.

Our partners operate across many diverse markets including pharmaceuticals, speciality chemicals, food and drink, electronics and transportation.

Why this role is important for CPI’s work

There are multiple vacancies available, each an exciting opportunity to become involved in process development and manufacturing evaluation of the Imperial college London vaccine. 

You will be responsible for developing an expertise in downstream processing of biopharmaceuticals, such as; proteins, viral vectors, nucleic-acid based products expressed in mammalian, bacterial or cell-free systems. Duties of the role include: 

  • To be involved / lead project experimentation to develop and optimise recovery and purification processes for the manufacture of biopharmaceutical products
  • Understanding of protein biochemistry; stability, folding, degradation and aggregation
  • Development of chromatography-based processing methods (affinity, IEX, HIC) and tangential flow filtration (TFF) techniques
  • Use of AKTA expression systems
  • Application of analysis of proteins or other biologics
  • Ensure work is to cGMP and maintain documented compliance with HSE
  • Documentation writing, data interpretation and statistical analysis
  • Assist the scale up of downstream processes to provide proof of successful process development

There are both permanent and fixed term (for 12 months) opportunities available. For full details of the role, and the associated responsibilities please refer to the Job Descriptions. 

The person we are seeking

We are looking to recruit individuals from a Junior Scientist level through to a Principal Scientist level. We are looking for individuals who have: 

  • cGMP experience in a bio/​pharmaceutical manufacturing or R&D setting
  • Experience in protein purification
  • Experience of using AKTA expression systems and column chromatography is highly desirable
  • For Senior Scientist and Principal Scientist, project lead experience is necessary

For more details about the requirements and expectations for each level, please refer to the Job Descriptions. 

What does CPI offer you?

At CPI, we offer a wide range of benefits to our employees, including: family friendly policies, flexible holidays and holiday purchasing schemes, opportunities for learning and development, generous pension plan, life assurance and accident insurance schemes.

Additional information

All applicants must have the legal right to live and work in the UK at the time of application. Presentation of appropriate original documents will be required.

Apply for the Job

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Applying takes 3 simple steps. We don’t anticipate any issues but if you have any please email recruitment@uk-cpi.com

Eligibility to Work in the UK

Please provide some information about your eligibility to work in the UK

Sorry we can’t take your application further as you don’t meet the eligibility criteria for the role. If you have any queries relating to this please email recruitment@uk-cpi.com