Principal Scientist — Biologics

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Job Details

Location
Darlington, England
Salary
£45,000 - £61,000 per annum- dependent on experience
Employment
Full-time - Permanent
Team
Science and Engineering
Deadline
14 Dec 2022 - 23:45
Reference
CPI-6382-22
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About CPI

CPI helps make great ideas and inventions a reality. We’re a team of intelligent people using advances in science and technology to solve the biggest global challenges in healthcare and sustainability.

Through our incredible people and innovation infrastructure, we collaborate with our partners in industry, academia, government, and the investment community to accelerate the development and commercialisation of innovative products.

From health technologies and pharmaceuticals to sustainable food and materials innovations, we turn the entrepreneurial spirit and radical thinking of our people and partners into incredible impact that makes our world a better place.

Why this role is important for CPI’s work

CPI helps make great ideas and inventions a reality. We’re a team of motivated people using advances in science and technology to solve the biggest global challenges in healthcare and sustainability.

Our incredible people collaborate with our partners in industry, academia, government, and the investment community to accelerate the development and commercialisation of innovative products.

From health technologies and pharmaceuticals to sustainable food and materials innovations, we turn the entrepreneurial spirit and radical thinking of our people and partners into incredible impact that makes our world a better place.

At the state-of-the-art Biologics and RNA manufacturing facility in Darlington, our specialist scientists and engineers help our customers and collaborators bring their novel biological medicines to patients. We do this through the application of high-throughput technology and digital tools to innovate, de-risk, and accelerate development of the next generation of manufacturing platforms. We work with a range of biologic formats, from antibodies to viral vectors and RNA, leveraging process expertise to deliver the best outcome for our partners. In Biologics you would be joining an empowered, engaged, and diverse team, working cross-functionally and externally giving you the opportunity to develop your experience and career in a dynamic and stimulating environment. 

Case studies of our Biologics work, and impact are linked below:

We have recently shared project successes at events including:

  • mRNA Manufacturing Summit – Boston
  • ECI Integrated Continuous Biomanufacturing V – Barcelona
  • Bioprocess UK – Edinburgh
  • PEGS Europe — Barcelona

Role

We are looking to appoint a Principal Scientist to lead projects within the Biologics business unit in Darlington. The person in the role will work to support clients and partner in upstream and/​or downstream processing and/​or analytical characterisation of biopharmaceuticals such as proteins, viral vectors, and nucleic-acid-based products expressed in mammalian, bacterial, insect, yeast cells and/​or cell-free systems.

The key responsibilities of this role are below. 

  • Theoretical and practical knowledge and expertise in Cell Biology, Biologics expression, Bioreactor scale up, and relevant analytical techniques (expert knowledge or understanding to support area of expertise). 
  • Theoretical and practical knowledge and expertise in Biochemistry, Biologics Purification, Biochemical Engineering, and relevant analytical techniques (expert knowledge or understanding to support area of expertise). 
  • Theoretical and practical knowledge and expertise in the development, utilisation, and verification of analytical methods for characterisation of in-process and final product biopharmaceuticals (expert knowledge or understanding to support area of expertise). 
  • Lead and deliver experimentation around the production and/​or analysis of therapeutic biologics focussed on the design, development, and scale-down/scale-up of upstream processes or the development and/​or adoption of new technologies
  • Knowledge, application, and use of CIP or reusable or single-use systems in Biologics 

The person we are seeking

You must have a broad knowledge/​expertise relevant to upstream and/​or downstream processing and/​or analytical characterisation of biopharmaceuticals such as proteins, viral vectors, and nucleic-acid based products expressed in mammalian, bacterial, insect, yeast cells and/​or cell-free systems. It would be desirable if you have an understanding of GMP requirements for the production of biopharmaceuticals.

What does CPI offer you?

At CPI, we offer a wide range of benefits to our employees, this includes:

  • Up to 36 days holiday, including bank holidays – Plus a holiday purchasing scheme
  • Generous pension scheme
  • Life assurance and accident insurance schemes
  • Flexible working
  • Learning and Development Opportunities
  • Free parking

Find out more about our culture and benefits.

Additional information

CPI is an organisation based in the UK. Commencement of employment is conditional to demonstrating right to work in the UK, sponsorship may be available.

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